ArticleF1000 biology reports2009
Monte Carlo, harmonic approximation, and coarse-graining approaches for enhanced sampling of biomolecular structure.
Article in F1000 biology reports, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
4 citing papers in PubMed.
- Biomolecular Modeling and Simulation: A Prospering Multidisciplinary Field.Annual review of biophysics · 2021Article
- Biomolecularmodeling and simulation: a field coming of age.Quarterly reviews of biophysics · 2011Review
- Thermal nanostructure: an order parameter multiscale ensemble approach.The Journal of chemical physics · 2010Article
- Molecular dynamics-based approaches for enhanced sampling of long-time, large-scale conformational changes in biomolecules.F1000 biology reports · 2009Article
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Authors and funding
1 author.
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Abstract
The rugged energy landscape of biomolecules and associated large-scale conformational changes have triggered the development of many innovative enhanced sampling methods, either based or not based on molecular dynamics (MD) simulations. Surveyed here are methods in the latter class - including Monte Carlo methods, harmonic approximations, and coarse graining - many of which yield valuable conformational insights into biomolecular structure and flexibility, despite altered kinetics. MD-based methods are surveyed in an upcoming issue of F1000 Biology Reports.
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Registered trials
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