Evidence map›Paper›PMID 20948558›Full record

ArticleEuropean journal of clinical nutrition2011

Diet and hip fractures among elderly Europeans in the EPIC cohort.

V Benetou, P Orfanos, D Zylis, S Sieri, P Contiero, R Tumino, M C Giurdanella, P H M Peeters, J Linseisen, A Nieters and 8 more

Abstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in European journal of clinical nutrition, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 10 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 10 pooled it
3.3field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 10 syntheses or guidelines pooled it, 56 citations in OpenAlex.

  1. Fatty acid dietary intakes and blood concentrations in relation to hip fracture risk in adults: a systematic review and meta-analysis of prospective cohort studies.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2025
    Pooled it
  2. Association between total and animal proteins with risk of fracture: A systematic review and dose-response meta-analysis of cohort studies.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2024
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  6. Dietary fat, saturated fatty acid, and monounsaturated fatty acid intakes and risk of bone fracture: a systematic review and meta-analysis of observational studies.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2018
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  11. Plasma fatty acid composition predicts bone mineral accrual from childhood to adolescence: the Physical Activity and Nutrition in Children study.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 12 institutions in 8 countries.

V BenetouDepartment of Hygiene, University of Athens Medical School, Athens, Greece. vben@nut.uoa.gr
P Orfanos
D Zylis
S Sieri
P Contiero
R Tumino
M C Giurdanella
P H M Peeters
J Linseisen
A Nieters
H Boeing
C Weikert
U Pettersson
I Johansson
H B Bueno-de-Mesquita
M Dorronsoro
P Boffetta
A Trichopoulou
Azienda Usl 8 Arezzo · ITGerman Institute of Human Nutrition · DENational and Kapodistrian University of Athens · GRUmeå University · SEAthens State University · USBasque Government · ESCentre International de Recherche sur le Cancer · FRFondazione IRCCS Istituto Nazionale dei Tumori · ITGerman Cancer Research Center · DEHellenic Health Foundation · GRNational Institute for Public Health and the Environment · NLUniversity Medical Center Utrecht · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

objectivesEvidence on the role of diet during adulthood and beyond on fracture occurrence is limited. We investigated diet and hip fracture incidence in a population of elderly Europeans, participants in the European Prospective Investigation into Cancer and nutrition study. SUBJECTS/

methods29, 122 volunteers (10,538 men, 18,584 women) aged 60 years and above (mean age: 64.3) from five countries were followed up for a median of 8 years and 275 incident hip fractures (222 women and 53 men) were recorded. Diet was assessed at baseline through validated dietary questionnaires. Data were analyzed through Cox proportional-hazards regression with adjustment for potential confounders.

resultsNo food group or nutrient was significantly associated with hip fracture occurrence. There were suggestive inverse associations, however, with vegetable consumption (hazard ratio (HR) per increasing sex-specific quintile: 0.93, 95% confidence interval (CI): 0.85-1.01), fish consumption (HR per increasing sex-specific quintile: 0.93, 95% CI: 0.85-1.02) and polyunsaturated lipid intake (HR per increasing sex-specific quintile: 0.92, 95% CI: 0.82-1.02), whereas saturated lipid intake was positively associated with hip fracture risk (HR per increasing sex-specific quintile: 1.13, 95% CI: 0.99-1.29). Consumption of dairy products did not appear to influence the risk (HR per increasing sex-specific quintile: 1.02, 95% CI: 0.93-1.12).

conclusionsIn a prospective study of the elderly, diet, including consumption of dairy products, alcohol and vitamin D, did not appear to play a major role in hip fracture incidence. There is however, weak and statistically non-significant evidence that vegetable and fish consumption and intake of polyunsaturated lipids may have a beneficial, whereas saturated lipid intake a detrimental effect.

Indexed as

DietFeeding BehaviorAgedAged, 80 and overEuropeFatty Acids, UnsaturatedFemaleHip FracturesHumansIncidenceMaleMiddle AgedNutrition AssessmentProportional Hazards ModelsProspective StudiesRisk FactorsFatty Acids, Unsaturated

Identifiers

PMID20948558
OpenAlexW2063929404

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.