Evidence map›Paper›PMID 20948499›Full record

ArticleMolecules (Basel, Switzerland)2010

Inhibitory effects of resveratrol on the Epstein-Barr virus lytic cycle.

Ching-Yi Yiu, Shih-Ying Chen, Li-Kwan Chang, Ya-Fang Chiu, Tsuey-Pin Lin

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 1 synthesis or guideline pooled it, 65 citations in OpenAlex.

  1. Pooled it
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  12. Antiviral activity of medicinal plant-derived products against SARS-CoV-2.Experimental biology and medicine (Maywood, N.J.) · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Ching-Yi YiuDepartment of Otolaryngology, Chi Mei Medical Center, Liouying, Tainan 717, Taiwan.
Shih-Ying Chen
Li-Kwan Chang
Ya-Fang Chiu
Tsuey-Pin Lin
Chia Nan University of Pharmacy and Science · TWChang Gung University · TWChi Mei Medical Center · TWNational Taiwan University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Reactivation of Epstein-Barr virus (EBV) from latency to the lytic cycle is required for the production of viral particles. Here, we examine the capacity of resveratrol to inhibit the EBV lytic cycle. Our results show that resveratrol inhibits the transcription of EBV immediate early genes, the expression of EBV lytic proteins, including Rta, Zta, and EA-D and reduces viron production, suggesting that this compound may be useful for preventing the proliferation of the virus.

Indexed as

Herpesvirus 4, HumanAnimalsAntioxidantsCell LineGenes, Immediate-EarlyHumansResveratrolStilbenesTranscription, GeneticViral ProteinsVirionVirus ReplicationAntioxidantsResveratrolStilbenesViral Proteins

Identifiers

PMID20948499
PMCPMC6259417
OpenAlexW1964846721

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.