ReviewProceedings of the Japan Academy. Series B, Physical and biological sciences2010
Molecular biology of histidine decarboxylase and prostaglandin receptors.
Review in Proceedings of the Japan Academy. Series B, Physical and biological sciences, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
15 citing papers in PubMed, 35 citations in OpenAlex.
- Article
- Review
- Article
- Function and Role of Histamine HPharmaceuticals (Basel, Switzerland) · 2023Review
- ELK4 exerts opposite roles in cytokine/chemokine production and degranulation in activated mast cells.Frontiers in immunology · 2023Article
- Review
- Lipopolysaccharide-induced expansion of histidine decarboxylase-expressing Ly6GScientific reports · 2019Article
- The transcription factors GATA2 and microphthalmia-associated transcription factor regulate Hdc gene expression in mast cells and are required for IgE/mast cell-mediated anaphylaxis.The Journal of allergy and clinical immunology · 2018Article
- High throughput data analyses of the immune characteristics of Microtus fortis infected with Schistosoma japonicum.Scientific reports · 2017Article
- Regulation of plasma histamine levels by the mast cell clock and its modulation by stress.Scientific reports · 2017Article
- The STAT5-GATA2 pathway is critical in basophil and mast cell differentiation and maintenance.Journal of immunology (Baltimore, Md. : 1950) · 2015Article
- Identification of histamine receptor subtypes in skeletal myogenesis.Molecular medicine reports · 2015Article
- Inhibitory activity of the flower buds of Lonicera japonica Thunb. against histamine production and L-histidine decarboxylase in human keratinocytes.Molecules (Basel, Switzerland) · 2014Article
- Prostaglandin E2 EP receptors as therapeutic targets in breast cancer.Cancer metastasis reviews · 2011Review
- Agonist-independent GαThe Journal of biological chemistryArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Histamine and prostaglandins (PGs) play a variety of physiological roles as autacoids, which function in the vicinity of their sources and maintain local homeostasis in the body. They stimulate target cells by acting on their specific receptors, which are coupled to trimeric G proteins. For the precise understanding of the physiological roles of histamine and PGs, it is necessary to clarify the molecular mechanisms involved in their synthesis as well as their receptor-mediated responses. We cloned the cDNAs for mouse L-histidine decarboxylase (HDC) and 6 mouse prostanoid receptors (4 PGE(2) receptors, PGF receptor, and PGI receptor). We then characterized the expression patterns and functions of these genes. Furthermore, we established gene-targeted mouse strains for HDC and PG receptors to explore the novel pathophysiological roles of histamine and PGs. We have here summarized our research, which should contribute to progress in the molecular biology of HDC and PG receptors.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.