Evidence map›Paper›PMID 20947862›Full record

ArticleCirculation research2010

Does oxidative DNA damage cause atherosclerosis and metabolic syndrome?: new insights into which came first: the chicken or the egg.

Nageswara R Madamanchi, Rui-Hai Zhou, Aleksandr E Vendrov, Xi-Lin Niu, Marschall S Runge

Abstract readEditorialComment
In one paragraph

Article in Circulation research, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Neutrophil Extracellular Traps in Atherosclerosis: Research Progress.International journal of molecular sciences · 2025
    Review
  2. Review
  3. Article
  4. Article
  5. Foam cells and the pathogenesis of kidney disease.Current opinion in nephrology and hypertension · 2015
    Review
  6. Macrophage functions in atherosclerosis.Circulation research · 2014
    Review
  7. Article
  8. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Nageswara R Madamanchi
Rui-Hai Zhou
Aleksandr E Vendrov
Xi-Lin Niu
Marschall S Runge

Funding

OXIDATIVE STRESS AND VASCULAR AGINGP01AG024282 · NIA · UNIV OF NORTH CAROLINA CHAPEL HILL · PI CLEMMONS, DAVID ROBERT · 2004 to 2008
$7.4M
Vasoactive Agonists, Oxidative Stress &AtherosclerosisR01HL057352 · NHLBI · UNIVERSITY OF TEXAS MEDICAL BR GALVESTON · PI RUNGE, MARSCHALL S. · 1997 to 2005
$1.6M
NHLBI NIH HHS R01 HL057352NIA NIH HHS P01 AG024282
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AtherosclerosisDNA DamageHumansMetabolic SyndromeOxidative Stress

Identifiers

PMID20947862
PMCPMC2975610

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.