ArticleJournal of the American Society of Nephrology : JASN2010
Age, race, diabetes, blood pressure, and mortality among hemodialysis patients.
Article in Journal of the American Society of Nephrology : JASN, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 2 of them syntheses that pooled it.
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Who cites it
41 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Management of blood pressure in adults, children and young people on dialysis: UK kidney association clinical practice guideline.BMC nephrology · 2025Guideline
- Management of Patient Care in Hemodialysis While Focusing on Cardiovascular Disease Events and the Atypical Role of Hyper- and/or Hypotension: A Systematic Review.BioMed research international · 2016Pooled it
- Safety and Efficacy of Losartan 50 mg in Reducing Blood Pressure among Patients with Post-Dialysis Euvolemic Hypertension: A Randomized Control Trial.Scientific reports · 2017Trial
- Trial
- Efficacy of Losartan in the management of Post-Dialysis Euvolemic Hypertension (HELD-Trial): A Single-Blind Randomized Control Trial.Scientific reports · 2016Trial
- Intensive vs Standard Blood Pressure Lowering in People With and Without Chronic Kidney Disease: A Systematic Review and Meta-Analysis.JAMA cardiology · 2026Article
- Article
- Using latent variables to improve the management of depression among hemodialysis patients.Renal failure · 2024Article
- Cardiovascular disease in waitlisted hemodialyzed patients.Renal failure · 2024Article
- Fasting blood glucose and the risk of all-cause mortality in patients with diabetes mellitus undergoing hemodialysis.Kidney research and clinical practice · 2024Article
- Regional variation in pre-dialysis blood pressure and its association with cardiovascular mortality rates in Japanese patients undergoing dialysis.Hypertension research : official journal of the Japanese Society of Hypertension · 2024Article
- Effect of Limb Salvage by Excimer Laser Angioplasty Plus Low-Pressure Balloon Inflation in Chronic Limb-Threatening Ischemia Patients with Infrapopliteal Vessel Disease.Acta Cardiologica Sinica · 2023Article
- Application of deep learning to predict the low serum albumin in new hemodialysis patients.Nutrition & metabolism · 2023Article
- Anemia biomarkers and mortality in hemodialysis patients with or without diabetes: A 10-year follow-up study.PloS one · 2023Article
- Hypertension in Dialysis Patients: Diagnostic Approaches and Evaluation of Epidemiology.Diagnostics (Basel, Switzerland) · 2022Review
- Epidemiology of haemodialysis outcomes.Nature reviews. Nephrology · 2022Review
- Tight Blood Pressure Control in Chronic Kidney Disease.Journal of cardiovascular development and disease · 2022Review
- Variability in Hemoglobin Levels and the Factors Associated with Mortality in Hemodialysis Patients: A 78-Month Follow-Up Study.International journal of environmental research and public health · 2021Article
- Postdialysis blood pressure is a better predictor of mortality than predialysis blood pressure in Japanese hemodialysis patients: the Japan Dialysis Outcomes and Practice Patterns Study.Hypertension research : official journal of the Japanese Society of Hypertension · 2020Article
- Alteration autonomic control of cardiac function during hemodialysis predict cardiovascular outcomes in end stage renal disease patients.Scientific reports · 2019Article
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7 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Observational studies involving hemodialysis patients suggest a U-shaped relationship between BP and mortality, but the majority of these studies followed large, heterogeneous cohorts. To examine whether age, race, and diabetes status affect the association between systolic BP (SBP; predialysis) and mortality, we studied a cohort of 16,283 incident hemodialysis patients. We constructed a series of multivariate proportional hazards models, adding age and BP to the analyses as cubic polynomial splines to model potential nonlinear relationships with mortality. Overall, low SBP associated with increased mortality, and the association was more pronounced among older patients and those with diabetes. Higher SBP associated with increased mortality among younger patients, regardless of race or diabetes status. We observed a survival advantage for black patients primarily among older patients. Diabetes associated with increased mortality mainly among older patients with low BP. In conclusion, the design of randomized clinical trials to identify optimal BP targets for patients with ESRD should take age and diabetes status into consideration.
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