Trial reportBreast cancer research and treatment2011
The benefits of discussing adjuvant therapies one at a time instead of all at once.
Trial report in Breast cancer research and treatment, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 1 synthesis or guideline pooled it, 48 citations in OpenAlex.
- Communicating treatment risks and benefits to cancer patients: a systematic review of communication methods.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2020Pooled it
- Persuasive Interventions for Controversial Cancer Screening Recommendations: Testing a Novel Approach to Help Patients Make Evidence-Based Decisions.Annals of family medicine · 2017Trial
- Presenting Numeric Information with Percentages and Descriptive Risk Labels: A Randomized Trial.Medical decision making : an international journal of the Society for Medical Decision Making · 2015Trial
- Too many cooks could spoil the broth: choice overload and the provision of ambulatory health care.International journal of health economics and management · 2024Article
- Article
- Cocreation with Dutch patients of decision-relevant information to support shared decision-making about adjuvant treatment in breast cancer care.Health expectations : an international journal of public participation in health care and health policy · 2022Article
- Risk Ladder, Table, or Bulleted List? Identifying Formats That Effectively Communicate Personalized Risk and Risk Reduction Information for Multiple Diseases.Medical decision making : an international journal of the Society for Medical Decision Making · 2021Article
- Keeping the patient in the center: Common challenges in the practice of shared decision making.Patient education and counseling · 2018Article
- Improving the Understanding of Test Results by Substituting (Not Adding) Goal Ranges: Web-Based Between-Subjects Experiment.Journal of medical Internet research · 2018Article
- Graphics help patients distinguish between urgent and non-urgent deviations in laboratory test results.Journal of the American Medical Informatics Association : JAMIA · 2017Article
- Subjective Numeracy and the Influence of Order and Amount of Audible Information on Perceived Medication Value.Medical decision making : an international journal of the Society for Medical Decision Making · 2017Article
- Article
- Patient educational technologies and their use by patients diagnosed with localized prostate cancer.BMC health services research · 2015Observational
- Numeracy and literacy independently predict patients' ability to identify out-of-range test results.Journal of medical Internet research · 2014Article
- Blocks, ovals, or people? Icon type affects risk perceptions and recall of pictographs.Medical decision making : an international journal of the Society for Medical Decision Making · 2014Article
- Article
- Physician communication styles in initial consultations for hematological cancer.Patient education and counseling · 2013Article
- How could disclosing incidental information from whole-genome sequencing affect patient behavior?Personalized medicine · 2013Article
- More Is Not Always Better: Intuitions About Effective Public Policy Can Lead to Unintended Consequences.Social issues and policy review · 2013Article
- Presenting quantitative information about decision outcomes: a risk communication primer for patient decision aid developers.BMC medical informatics and decision making · 2013Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
Breast cancer patients must often decide between multiple adjuvant therapy options to prevent cancer recurrence. Standard practice, as implemented in current decision support tools, is to present information about all options simultaneously, but psychology research suggests that sequential decision processes might improve decision making. We tested whether asking women to consider hormonal therapy and chemotherapy separately would improve women's risk knowledge and/or affect treatment intentions. We conducted an Internet-administered experimental survey of a demographically diverse sample of 1,781 women ages 40-74. Participants were randomized to experience a standard, comprehensive decision process versus sequential (one at a time) decisions regarding adjuvant therapy options for a hypothetical breast cancer patient with an estrogen receptor-positive (ER+) tumor. We assessed comprehension of key statistics, perceptions of treatment effectiveness, and perceived interest in adjuvant chemotherapy, as well as participants' numeracy levels. When participants made sequential decisions, they demonstrated greater comprehension of decision-relevant risk statistics, as compared to when they made decisions all at once (all P's < 0.001). Among higher-numeracy participants, those making sequential decisions were less interested in chemotherapy (P < 0.001). Lower-numeracy participants who considered all options simultaneously were insensitive to the degree of risk reduction, but those who made sequential decisions were sensitive (P = 0.03). In conclusion, presenting adjuvant therapy options sequentially improves women's comprehension of incremental treatment benefit and increases less numerate women's sensitivity to the magnitude of the achievable risk reduction over standard, all at once approaches. Sequential approaches to adjuvant therapy decisions may reduce use of chemotherapy among those at low risk for recurrence.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.