ArticleNature biotechnology2010
Epigenomics reveals a functional genome anatomy and a new approach to common disease.
Article in Nature biotechnology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
55 citing papers in PubMed.
- One-carbon metabolism and cardiovascular disease: Molecular mechanisms, genetic influences, and epigenetic regulation.Biochemistry and biophysics reports · 2026Review
- Omics-based large language models: A new engine for drug discovery innovation.Acta pharmaceutica Sinica. B · 2026Review
- Epigenetics in Glaucoma.Medicina (Kaunas, Lithuania) · 2024Review
- Role of Epigenetics in Type 2 Diabetes and Obesity.Biomedicines · 2021Review
- Blood DNA methylation biomarkers of cumulative lead exposure in adults.Journal of exposure science & environmental epidemiology · 2021Article
- An Updated Review of the Epigenetic Mechanism Underlying the Pathogenesis of Age-related Macular Degeneration.Aging and disease · 2020Review
- Significant association between DHFR promoter methylation and ischemic stroke in a Chinese hypertensive population.Journal of clinical laboratory analysis · 2020Article
- DNA Methylation-Based Biomarkers of Environmental Exposures for Human Population Studies.Current environmental health reports · 2020Review
- Building Skills and Resources for Genomics, Epigenetics, and Bioinformatics Research for Africa: Report of the Joint 11th Conference of the African Society of Human Genetics and 12th H3Africa Consortium, 2018.The American journal of tropical medicine and hygiene · 2020Article
- Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition).European journal of immunology · 2019Article
- CBS promoter hypermethylation increases the risk of hypertension and stroke.Clinics (Sao Paulo, Brazil) · 2019Article
- Stochastic phenotype switching leads to intratumor heterogeneity in human liver cancer.Hepatology (Baltimore, Md.) · 2018Article
- Human Lung DNA Methylation Quantitative Trait Loci Colocalize with Chronic Obstructive Pulmonary Disease Genome-Wide Association Loci.American journal of respiratory and critical care medicine · 2018Article
- Identification and caste-dependent expression patterns of DNA methylation associated genes in Bombus terrestris.Scientific reports · 2018Article
- Ensemble genomic analysis in human lung tissue identifies novel genes for chronic obstructive pulmonary disease.Human genomics · 2018Article
- Genomic 5-mC contents in peripheral blood leukocytes were independent protective factors for coronary artery disease with a specific profile in different leukocyte subtypes.Clinical epigenetics · 2018Article
- Rapid progression to glioblastoma in a subset of IDH-mutated astrocytomas: a genome-wide analysis.Journal of neuro-oncology · 2017Article
- Epigenetic modifications of interleukin-6 in synovial fibroblasts from osteoarthritis patients.Scientific reports · 2017Article
- Precision medicine driven by cancer systems biology.Cancer metastasis reviews · 2017Article
- DNA methylation profiling in human lung tissue identifies genes associated with COPD.Epigenetics · 2016Article
Corrections and comments
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Authors and funding
1 author.
Funding
Abstract
Epigenomics provides the context for understanding the function of genome sequence, analogous to the functional anatomy of the human body provided by Vesalius a half-millennium ago. Much of the seemingly inconclusive genetic data related to common diseases could therefore become meaningful in an epigenomic context.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.