Evidence map›Paper›PMID 20944227›Full record

ArticleActa crystallographica. Section F, Structural biology and crystallization communications2010

Ligands in PSI structures.

Abhinav Kumar, Hsiu Ju Chiu, Herbert L Axelrod, Andrew Morse, Marc André Elsliger, Ian A Wilson, Ashley Deacon

Abstract read
In one paragraph

Article in Acta crystallographica. Section F, Structural biology and crystallization communications, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Ligand placement based on prior structures: the guided ligand-replacement method.Acta crystallographica. Section D, Biological crystallography · 2014
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. The JCSG high-throughput structural biology pipeline.Acta crystallographica. Section F, Structural biology and crystallization communications · 2010
    Article
  11. Structure of a tryptophanyl-tRNA synthetase containing an iron-sulfur cluster.Acta crystallographica. Section F, Structural biology and crystallization communications · 2010
    Article
  12. Ligands in crystal structures that aid in functional characterization.Acta crystallographica. Section F, Structural biology and crystallization communications · 2010
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Abhinav KumarStanford Synchrotron Radiation Lightsource, SLAC National Accelerator Laboratory, Menlo Park, CA, USA.
Hsiu Ju Chiu
Herbert L Axelrod
Andrew Morse
Marc André Elsliger
Ian A Wilson
Ashley Deacon

Funding

Technology Evaluation CoreU54GM074898 · NIGMS · SCRIPPS RESEARCH INSTITUTE, THE · PI WILSON, IAN A · 2005 to 2009
$50.6M
NIGMS NIH HHS U54 GM074898
6 · The paper itself

Abstract

Approximately 65% of PSI structures report some type of ligand(s) that is bound in the crystal structure. Here, a description is given of how such ligands are handled and analyzed at the JCSG and a survey of the types, variety and frequency of ligands that are observed in the PSI structures is also compiled and analyzed, including illustrations of how these bound ligands have provided functional clues for annotation of proteins with little or no previous experimental characterization. Furthermore, a web server was developed as a tool to mine and analyze the PSI structures for bound ligands and other identifying features.

Indexed as

Databases, GeneticCrystallography, X-RayInternetLigandsModels, MolecularProtein ConformationLigands

Identifiers

PMID20944227
PMCPMC2954221

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.