Evidence map›Paper›PMID 20943879›Full record

ArticleClinical and vaccine immunology : CVI2010

Antibody responses in mice stimulated by various doses of the potato-derived major surface antigen of hepatitis B virus.

Jung Won Youm, Young Suk Won, Jae Heung Jeon, Ki Beom Moon, Hyoung Chin Kim, Kee-Sun Shin, Hyouk Joung, Hyun Soon Kim

Abstract read
In one paragraph

Article in Clinical and vaccine immunology : CVI, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Review
  6. Review
  7. Induced immunity against hepatitis B virus.World journal of hepatology · 2015
    Review
  8. Production of pharmaceutical proteins in solanaceae food crops.International journal of molecular sciences · 2013
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jung Won YoumPlant Genome Research Center, KRIBB, 111 Gwahangno, Yuseong-gu, Daejeon 305-806, Republic of Korea.
Young Suk Won
Jae Heung Jeon
Ki Beom Moon
Hyoung Chin Kim
Kee-Sun Shin
Hyouk Joung
Hyun Soon Kim

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The ability of potato-derived major surface antigen of hepatitis B virus (P-HBsAg) to elicit antibody responses to different dosages of P-HBsAg ranging from 0.02 to 30 μg administered orally in mice was examined. All immunized groups produced specific serum IgG and fecal IgA antibodies against P-HBsAg, even at low levels (<5 μg), after administration of a 0.5-μg yeast-derived HBsAg (Y-HBsAg; LG Life Sciences, Republic of Korea) booster.

Indexed as

Administration, OralAnimalsBloodHepatitis B AntibodiesHepatitis B Surface AntigensHepatitis B VaccinesImmunoglobulin AImmunoglobulin GIntestinal MucosaMicePlants, Genetically ModifiedRepublic of KoreaSolanum tuberosumVaccines, SyntheticHepatitis B AntibodiesHepatitis B Surface AntigensHepatitis B VaccinesImmunoglobulin AImmunoglobulin GVaccines, Synthetic

Identifiers

PMID20943879
PMCPMC3008205

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.