Evidence map›Paper›PMID 20943869›Full record

ArticleJournal of clinical microbiology2010

Evaluation of molecular assays for rapid detection of methicillin-resistant Staphylococcus aureus.

Surbhi Malhotra-Kumar, Liesbet Van Heirstraeten, Andie Lee, José Cortinas Abrahantes, Christine Lammens, Evelyn Vanhommerig, Geert Molenberghs, Marc Aerts, Stephan Harbarth, Herman Goossens and 1 more

Open access · greenAbstract readComparative StudyEvaluation Study
In one paragraph

Article in Journal of clinical microbiology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 30 citations in OpenAlex.

  1. Trial
  2. Review
  3. Resistance-Guided Therapy for Neisseria gonorrhoeae.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2022
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Positive predictive value of the Xpert MRSA assay diagnostic for universal patient screening at hospital admission: influence of the local ecology.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2012
    Article
  10. Are we ready for novel detection methods to treat respiratory pathogens in hospital-acquired pneumonia?Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2011
    Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Surbhi Malhotra-KumarDepartment of Medical Microbiology, Vaccine & Infectious Disease Institute, Campus Drie Eiken, University of Antwerp, S3, Universiteitsplein 1, B-2610 Wilrijk, Antwerp, Belgium. surbhi.malhotra@ua.ac.be
Liesbet Van Heirstraeten
Andie Lee
José Cortinas Abrahantes
Christine Lammens
Evelyn Vanhommerig
Geert Molenberghs
Marc Aerts
Stephan Harbarth
Herman Goossens
MOSAR WP2 Study Team
University of Antwerp · BEHasselt University · BEUniversity of Geneva · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The diagnostic sensitivities of the BD GeneOhm and Cepheid Xpert assays were compared using culture on log-serial dilutions of well-characterized methicillin-resistant Staphylococcus aureus (MRSA) and non-MRSA strains and on nasal and groin swabs from patients with histories of MRSA carriage. The sensitivities of GeneOhm and Xpert were high at 10(3)-CFU/ml MRSA concentrations (92.3% and 96.3%, respectively) although decreased considerably (<35%) at a 1-log-lower concentration. Unexpectedly, both assays also detected select coagulase-negative staphylococci, which requires further evaluation.

Indexed as

Bacteriological TechniquesCarrier StateCoagulaseGroinHumansMethicillin-Resistant Staphylococcus aureusMolecular Diagnostic TechniquesNasal MucosaSensitivity and SpecificityStaphylococcal InfectionsCoagulase

Identifiers

PMID20943869
PMCPMC3008470
OpenAlexW2156144327

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.