ArticleJournal of the Royal Society, Interface2011
Targeting vaccination against novel infections: risk, age and spatial structure for pandemic influenza in Great Britain.
Article in Journal of the Royal Society, Interface, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
25 citing papers in PubMed, 48 citations in OpenAlex.
- Optimal control prevents itself from eradicating stochastic disease epidemics.PLoS computational biology · 2025Article
- Understanding the impact of disease and vaccine mechanisms on the importance of optimal vaccine allocation.Infectious Disease Modelling · 2023Article
- Asymptotic Analysis of Optimal Vaccination Policies.Bulletin of mathematical biology · 2023Article
- Non-pharmaceutical interventions and their relevance in the COVID-19 vaccine rollout in Saudi Arabia and Arab Gulf countries.Infectious Disease Modelling · 2022Article
- A decision support system for prioritised COVID-19 two-dosage vaccination allocation and distribution.Transportation research. Part E, Logistics and transportation review · 2022Article
- Influence of heterogeneous age-group contact patterns on critical vaccination rates for herd immunity to SARS-CoV-2.Scientific reports · 2022Article
- Structural identifiability analysis of age-structured PDE epidemic models.Journal of mathematical biology · 2022Article
- Local Characteristics Related to SARS-CoV-2 Transmissions in the Seoul Metropolitan Area, South Korea.International journal of environmental research and public health · 2021Article
- Fast Containment of Infectious Diseases With E-Healthcare Mobile Social Internet of Things.IEEE internet of things journal · 2021Article
- Modelling optimal vaccination strategy for SARS-CoV-2 in the UK.PLoS computational biology · 2021Article
- A theoretical single-parameter model for urbanisation to study infectious disease spread and interventions.PLoS computational biology · 2019Article
- Countering vaccine hesitancy through immunization information systems, a narrative review.Human vaccines & immunotherapeutics · 2019Review
- Equalizing access to pandemic influenza vaccines through optimal allocation to public health distribution points.PloS one · 2017Article
- Evaluating Hospital-Based Surveillance for Outbreak Detection in Bangladesh: Analysis of Healthcare Utilization Data.PLoS medicine · 2017Article
- Fine resolution mapping of population age-structures for health and development applications.Journal of the Royal Society, Interface · 2015Article
- Reactive vaccination in the presence of disease hotspots.Proceedings. Biological sciences · 2015Article
- Vaccine Induced Herd Immunity for Control of Respiratory Syncytial Virus Disease in a Low-Income Country Setting.PloS one · 2015Article
- The contribution of social behaviour to the transmission of influenza A in a human population.PLoS pathogens · 2014Article
- The Possible Impact of Vaccination for Seasonal Influenza on Emergence of Pandemic Influenza via Reassortment.PloS one · 2014Article
- Quantifying age-related rates of social contact using diaries in a rural coastal population of Kenya.PloS one · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
Abstract
The emergence of a novel strain of H1N1 influenza virus in Mexico in 2009, and its subsequent worldwide spread, has focused attention to the question of optimal deployment of mass vaccination campaigns. Here, we use three relatively simple models to address three issues of primary concern in the targeting of any vaccine. The advantages of such simple models are that the underlying assumptions and effects of individual parameters are relatively clear, and the impact of uncertainty in the parametrization can be readily assessed in the early stages of an outbreak. In particular, we examine whether targeting risk-groups, age-groups or spatial regions could be optimal in terms of reducing the predicted number of cases or severe effects; and how these targeted strategies vary as the epidemic progresses. We examine the conditions under which it is optimal to initially target vaccination towards those individuals within the population who are most at risk of severe effects of infection. Using age-structured mixing matrices, we show that targeting vaccination towards the more epidemiologically important age groups (5-14 year olds and then 15-24 year olds) leads to the greatest reduction in the epidemic growth and hence reduces the total number of cases. Finally, we consider how spatially targeting the vaccine towards regions of country worst affected could provide an advantage. We discuss how all three of these priorities change as both the speed at which vaccination can be deployed and the start of the vaccination programme is varied.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.