ArticleGenetics2010
The yeast mating-type switching mechanism: a memoir.
Article in Genetics, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- Review
- Cellular and metabolic engineering of oleaginous yeastEngineering in life sciences · 2019Review
- The Inherent Asymmetry of DNA Replication.Annual review of cell and developmental biology · 2017Review
- An Evolutionary Perspective on Yeast Mating-Type Switching.Genetics · 2017Review
- From Two to One: Unipolar Sexual Reproduction.Fungal biology reviews · 2015Article
- Article
- A Unique DNA Recombination Mechanism of the Mating/Cell-type Switching of Fission Yeasts: a Review.Microbiology spectrum · 2014Review
- Constraint and opportunity in genome innovation.RNA biology · 2014Review
- Homing endonucleases: from genetic anomalies to programmable genomic clippers.Methods in molecular biology (Clifton, N.J.) · 2014Review
- Schizosaccharomyces japonicus yeast poised to become a favorite experimental organism for eukaryotic research.G3 (Bethesda, Md.) · 2013Article
- Article
Corrections and comments
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Authors and funding
1 author.
Funding
Abstract
It has been 33 years since I first presented results of genetic experiments that established the gene transposition model as the mechanism of mating-type switching in the budding yeast Saccharomyces cerevisiae at the Cold Spring Harbor Laboratory (CSHL) Yeast Genetics meeting in August 1977. Over two decades ago the Genetics Perspectives editors solicited a perspective on my participation in the studies that deciphered the mechanism of mating-type switching and revealed the phenomenon of gene silencing in yeast. Although flattered at the time, I thought that preparation of such an article called for a more seasoned researcher who had benefitted from seeing his contributions stand the test of time. Now realizing that our discovery of the transposition of a mutation from the HMα locus into the MAT (mating type) locus has provided the genetic evidence that established the gene transposition model, and having witnessed our conclusions confirmed by subsequent molecular studies, I decided that perhaps this is a good time to recount the chronology of events as they unfolded for me decades ago.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.