Evidence map›Paper›PMID 20938865›Full record

ReviewJournal of trauma & dissociation : the official journal of the International Society for the Study of Dissociation (ISSD)2010

Posttraumatic oxytocin dysregulation: is it a link among posttraumatic self disorders, posttraumatic stress disorder, and pelvic visceral dysregulation conditions in women?

Julia S Seng

Abstract readReview
In one paragraph

Review in Journal of trauma & dissociation : the official journal of the International Society for the Study of Dissociation (ISSD), 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. A Pilot Study of Oxytocin in Low-Income Women With a Low Birth-Weight Infant: Is Oxytocin Related to Posttraumatic Stress?Advances in neonatal care : official journal of the National Association of Neonatal Nurses · 2019
    Article
  8. Article
  9. Review
  10. Article
  11. [Neurobiology of posttraumatic and somatoform disorders in the elderly].Zeitschrift fur Gerontologie und Geriatrie · 2014
    Article
  12. Exploring dissociation and oxytocin as pathways between trauma exposure and trauma-related hyperemesis gravidarum: a test-of-concept pilot.Journal of trauma & dissociation : the official journal of the International Society for the Study of Dissociation (ISSD) · 2013
    Article
  13. Article
  14. Prevalence and Predictors of Breastfeeding After Childhood Abuse.Journal of obstetric, gynecologic, and neonatal nursing : JOGNN
    Observational
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Julia S SengSchool of Nursing, Institute for Research on Women and Gender, Department of Obstetrics and Gynecology, and Department of Women's Studies, University of Michigan, Ann Arbor, Michigan 48109-1290, USA. jseng@umich.edu

Funding

ZINC GLUCONATE GLYCINE LOZENGES &VITAMIN C EFFECTS ON COMMON COLDM01RR000042 · NCRR · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI ELSTROM, REBECCA L · 1985 to 2007
$40.8M
PUBLIC HEALTH DEMONSTRATIONP60DK020572 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MYERS, MARTIN G · 1985 to 2012
$26.5M
Regional Pilot And Feasibility Study Grants ProgramP30DK020572 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI DAVID P OLSON · 2013 to 2026
$24.3M
PSYCHOBIOLOGY OF PTSD &ADVERSE OUTCOMES OF CHILDBEARINGR01NR008767 · NINR · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI SENG, JULIA S · 2005 to 2008
$2.1M
MESA Center for Health DisparitiesP20NR008367 · NINR · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI VILLARRUEL, ANTONIA M. · 2002 to 2006
$1.2M
NCRR NIH HHS M01 RR000042NCRR NIH HHS M01-RR00042NIDDK NIH HHS DK020572NIDDK NIH HHS P30 DK020572NIDDK NIH HHS P60 DK020572NINR NIH HHS 1P20 NR008367NINR NIH HHS P20 NR008367NINR NIH HHS R01 NR008767PHS HHS U013786
6 · The paper itself

Abstract

This article explicates a theory that oxytocin, a sexually dimorphic neurotransmitter and paracrine hormone, is a plausible mechanism linking early relational trauma with posttraumatic self disorders (e.g., dissociation, somatization, and interpersonal sensitivity), posttraumatic stress disorder, and pelvic visceral dysregulation disorders (e.g., irritable bowel syndrome, chronic pelvic pain, interstitial cystitis, and hyperemesis gravidarum). This posttraumatic oxytocin dysregulation disorders theory is consistent with the historical and contemporary literature. It integrates attention to psychological and physical comorbidities and could account for the increased incidence of these disorders among females. Specific propositions are explored in data from studies of traumatic stress and women's health.

Indexed as

Interpersonal RelationsCystitis, InterstitialDissociative DisordersFemaleHumansHyperemesis GravidarumIrritable Bowel SyndromeModels, PsychologicalModels, TheoreticalOxytocinPelvic PainPregnancyPregnancy ComplicationsPsychophysiologic DisordersSomatoform DisordersStress Disorders, Post-TraumaticOxytocin

Identifiers

PMID20938865
PMCPMC2975946

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.