Trial reportPediatrics2010
High mortality rates for very low birth weight infants in developing countries despite training.
Trial report in Pediatrics, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 7 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 7 syntheses or guidelines pooled it, 49 citations in OpenAlex.
- Standardised formal resuscitation training programmes for reducing mortality and morbidity in newborn infants.The Cochrane database of systematic reviews · 2026Pooled it
- Evidence-based interventions to reduce mortality among preterm and low-birthweight neonates in low-income and middle-income countries: a systematic review and meta-analysis.BMJ global health · 2021Pooled it
- The effects of interactive training of healthcare providers on the management of life-threatening emergencies in hospital.The Cochrane database of systematic reviews · 2019Pooled it
- Neonatal Mortality in Hospitalized Chinese Population: A Meta-Analysis.BioMed research international · 2019Pooled it
- Standardised formal resuscitation training programmes for reducing mortality and morbidity in newborn infants.The Cochrane database of systematic reviews · 2015Pooled it
- In-service training for health professionals to improve care of seriously ill newborns and children in low-income countries.The Cochrane database of systematic reviews · 2015Pooled it
- Preterm birth-associated neurodevelopmental impairment estimates at regional and global levels for 2010.Pediatric research · 2013Pooled it
- Benefits of neonatal resuscitation training in high- and low-resource settings.Seminars in fetal & neonatal medicine · 2026Review
- Neonatal Resuscitation Online Registry in Shenzhen: protocol for a prospective, multicentre, open, observational cohort study.BMJ open · 2024Observational
- Evaluating WHO-Recommended Interventions for Preterm Birth: A Mathematical Model of the Potential Reduction of Preterm Mortality in Sub-Saharan Africa.Global health, science and practice · 2019Article
- Preterm birth in evolutionary context: a predictive adaptive response?Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2019Review
- Care of the mother-infant dyad: a novel approach to conducting and evaluating neonatal resuscitation simulation training in Bihar, India.BMC pregnancy and childbirth · 2017Article
- Impact of neonatal resuscitation trainings on neonatal and perinatal mortality: a systematic review and meta-analysis.BMJ paediatrics open · 2017Article
- Cost analysis of large-scale implementation of the 'Helping Babies Breathe' newborn resuscitation-training program in Tanzania.BMC health services research · 2016Article
- Institutional deliveries and perinatal and neonatal mortality in Southern and Central India.Reproductive health · 2015Article
- Born too soon: care for the preterm baby.Reproductive health · 2013Review
- Neonatal death in low- to middle-income countries: a global network study.American journal of perinatology · 2012Article
- Cause-specific neonatal mortality in a neonatal care unit in Northern Tanzania: a registry based cohort study.BMC pediatrics · 2012Article
- Epidemiology of stillbirth in low-middle income countries: a Global Network Study.Acta obstetricia et gynecologica Scandinavica · 2011Article
Corrections and comments
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Authors and funding
20 authors at 15 institutions in 7 countries.
Funding
Abstract
objectiveThe goal was to determine the effect of training in newborn care and resuscitation on 7-day (early) neonatal mortality rates for very low birth weight (VLBW) infants. The study was designed to test the hypothesis that these training programs would reduce neonatal mortality rates for VLBW infants.
methodsLocal instructors trained birth attendants from 96 rural communities in 6 developing countries in protocol and data collection, the World Health Organization Essential Newborn Care (ENC) course, and a modified version of the American Academy of Pediatrics Neonatal Resuscitation Program (NRP), by using a train-the-trainer model. To test the impact of ENC training, data on infants of 500 to 1499 g were collected by using a before/after, active baseline, controlled study design. A cluster-randomized, controlled trial design was used to test the impact of the NRP.
resultsA total of 1096 VLBW (500-1499 g) infants were enrolled, and 98.5% of live-born infants were monitored to 7 days. All-cause, 7-day neonatal mortality, stillbirth, and perinatal mortality rates were not affected by ENC or NRP training.
conclusionsNeither ENC nor NRP training of birth attendants decreased 7-day neonatal, stillbirth, or perinatal mortality rates for VLBW infants born at home or at first-level facilities. Encouragement of delivery in a facility where a higher level of care is available may be preferable when delivery of a VLBW infant is expected.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.