ArticleAlimentary pharmacology & therapeutics2010
Risk of colorectal adenomas in patients with coeliac disease.
Article in Alimentary pharmacology & therapeutics, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.
- Colonic neoplasia and celiac disease: A systematic review.World journal of gastroenterology · 2025Pooled it
- Bidirectional Mendelian Randomization Analysis Reveals Causal Associations Between Autoimmune Diseases and Colorectal Cancer.World journal of oncology · 2026Article
- Malignancies in Celiac Disease-A Hidden Threat with Diagnostic Pitfalls.Biomedicines · 2025Review
- Prevalence of malignant neoplasms in celiac disease patients - a nationwide United States population-based study.World journal of clinical oncology · 2024Article
- Increased Risk of Colorectal Cancer in Patients With Celiac Disease: A Population-Based Study.Cureus · 2023Article
- Malignant complications of celiac disease: a case series and review of the literature.Journal of medical case reports · 2022Review
- Review
- Association between intestinal neoplasms and celiac disease: A review.World journal of gastrointestinal oncology · 2021Review
- Association Between Celiac Disease and Cancer.International journal of molecular sciences · 2020Review
- Colorectal Adenoma Risk Is Increased among Recently Diagnosed Adult Celiac Disease Patients.Gastroenterology research and practice · 2018Article
- Geographic trends and risk of gastrointestinal cancer among patients with celiac disease in Europe and Asian-Pacific region.Gastroenterology and hepatology from bed to bench · 2013Review
- Sex and racial disparities in duodenal biopsy to evaluate for celiac disease.Gastrointestinal endoscopy · 2012Article
- Increased sedation requirements during endoscopy in patients with celiac disease.Digestive diseases and sciences · 2012Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
backgroundCoeliac disease is associated with an increased risk of lymphoma and small bowel malignancy, but most studies have found no increased risk of colorectal cancer.
aimTo compare the prevalence of colorectal adenomas in coeliac disease patients with that in non-coeliac disease controls.
methodsWe identified all coeliac disease patients who underwent colonoscopy at our institution during a 44-month period. We matched each patient with non-coeliac disease controls by age, gender and endoscopist. We compared the adenoma prevalence between these groups, and used multivariate analysis to assess the independent association of coeliac disease with adenomas.
resultsWe identified 180 patients with coeliac disease and 346 controls. At least one adenoma was present in 13% of coeliac disease patients and 17% of controls (P = 0.20). On multivariate analysis, age (OR per year 1.04, 95% CI 1.02-1.07) and male gender (OR 2.33, 95% CI 1.36-3.98) were associated with adenomas, while the relationship between coeliac disease and adenomas remained null (OR 0.75, 95% CI 0.41-1.34).
conclusionsCoeliac disease is not associated with an increased risk of colorectal neoplasia. The lack of increased risk of colorectal cancer observed in population studies is related to a true average risk of colorectal neoplasia, rather than artifactually reflecting increased colonoscopy and associated polypectomies in the coeliac population.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.