Evidence map›Paper›PMID 20936972›Full record

ReviewAnnual review of immunology2011

Innate antifungal immunity: the key role of phagocytes.

Gordon D Brown

Abstract readReview
In one paragraph

Review in Annual review of immunology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 233 papers.

0numbers the graph read from it
0cells of the map it votes in
233citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

233 citing papers in PubMed.

  1. Trial
  2. mBio · 2026
    Article
  3. Review
  4. Review
  5. Review
  6. Phagosome maturation during fungal infection.Current opinion in microbiology · 2026
    Review
  7. Article
  8. A roadmap to chemically reactive species: how diverse oxidants affectMicrobiology and molecular biology reviews : MMBR · 2025
    Review
  9. Review
  10. Article
  11. Review
  12. Article
  13. Article
  14. Review
  15. Article
  16. Amphibian (Journal of fungi (Basel, Switzerland) · 2025
    Article
  17. Recent developments inMicrobiology and molecular biology reviews : MMBR · 2025
    Review
  18. Article
  19. Article
  20. Advancements in vaginal microbiota,Microbial cell (Graz, Austria) · 2025
    Review

173 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Gordon D BrownAberdeen Fungal Group, Section of Immunology and Infection, Division of Applied Medicine, Institute of Medical Sciences, University of Aberdeen, Foresterhill, United Kingdom. gordon.brown@abdn.ac.uk

Funding

Wellcome Trust 086558
6 · The paper itself

Abstract

Fungal diseases have emerged as significant causes of morbidity and mortality, particularly in immune-compromised individuals, prompting greater interest in understanding the mechanisms of host resistance to these pathogens. Consequently, the past few decades have seen a tremendous increase in our knowledge of the innate and adaptive components underlying the protective (and nonprotective) mechanisms of antifungal immunity. What has emerged from these studies is that phagocytic cells are essential for protection and that defects in these cells compromise the host's ability to resist fungal infection. This review covers the functions of phagocytes in innate antifungal immunity, along with selected examples of the strategies that are used by fungal pathogens to subvert these defenses.

Indexed as

FungiAdaptive ImmunityAnimalsHumansImmune EvasionImmunity, InnateMycosesPhagocytes

Identifiers

PMID20936972
PMCPMC3434799

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.