ArticleJournal of the American Chemical Society2010
Superresolution imaging of targeted proteins in fixed and living cells using photoactivatable organic fluorophores.
Article in Journal of the American Chemical Society, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 69 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
69 citing papers in PubMed.
- Phenoxazines with a PhototransferableJournal of the American Chemical Society · 2026Article
- A Fluorogenic Reaction for Monitoring Cross-Coupling with Turn-On Ratio Greater than a Hundred Thousand.Chemical & biomedical imaging · 2026Article
- Photoactivation of BODIPY Fluorescence with Green Light.The Journal of organic chemistry · 2025Article
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- Article
- Photoactivatable BODIPYs for Live-Cell PALM.Molecules (Basel, Switzerland) · 2023Review
- Recent biomedical advances enabled by HaloTag technology.Biocell : official journal of the Sociedades Latinoamericanas de Microscopia Electronica ... et. al · 2022Article
- Oxime as a general photocage for the design of visible light photo-activatable fluorophores.Chemical science · 2021Article
- Split-HaloTag imaging assay for sophisticated microscopy of protein-protein interactionsPlant communications · 2021Article
- Single-Molecule Tracking of Chromatin-Associated Proteins in theThe journal of physical chemistry. B · 2021Article
- Quantitative interrogation of protein co-aggregation using multi-color fluorogenic protein aggregation sensors.Chemical science · 2021Article
- Enzymatic Labeling of Bacterial Proteins for Super-resolution Imaging in Live Cells.ACS central science · 2019Article
- Protein Spin Labeling with a Photocaged Nitroxide Using Diels-Alder Chemistry.Chembiochem : a European journal of chemical biology · 2019Article
- Ultrasensitive magnetic resonance imaging of systemic reactive oxygen speciesChemical science · 2019Article
- Expanding the Chemical Space of Biocompatible Fluorophores: Nanohoops in Cells.ACS central science · 2018Article
- Switchable Fluorophores for Single-Molecule Localization Microscopy.Chemical reviews · 2018Review
- Optochemical Control of Biological Processes in Cells and Animals.Angewandte Chemie (International ed. in English) · 2018Review
- Molecular design of upconversion nanoparticles for gene delivery.Chemical science · 2017Review
- Breaking the color barrier - a multi-selective antibody reporter offers innovative strategies of fluorescence detection.Journal of cell science · 2017Article
- Photostable and photoswitching fluorescent dyes for super-resolution imaging.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2017Review
9 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors.
Funding
Abstract
Superresolution imaging techniques based on sequential imaging of sparse subsets of single molecules require fluorophores whose emission can be photoactivated or photoswitched. Because typical organic fluorophores can emit significantly more photons than average fluorescent proteins, organic fluorophores have a potential advantage in super-resolution imaging schemes, but targeting to specific cellular proteins must be provided. We report the design and application of HaloTag-based target-specific azido DCDHFs, a class of photoactivatable push-pull fluorogens which produce bright fluorescent labels suitable for single-molecule superresolution imaging in live bacterial and fixed mammalian cells.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.