ReviewPediatric nephrology (Berlin, Germany)2011
Acute kidney injury in childhood: should we be worried about progression to CKD?
Review in Pediatric nephrology (Berlin, Germany), 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
40 citing papers in PubMed, 88 citations in OpenAlex.
- Caregiver Perspectives for Pediatric Patients with Acute Kidney Injury on Dialysis: A Narrative Review.Journal of multidisciplinary healthcare · 2026Review
- From acute kidney injury to chronic kidney disease in children: maladaptive repair and the need for long-term surveillance - a literature review.BMC nephrology · 2025Review
- Association between blood cadmium levels and the risk of chronic kidney disease in Korea, based on the Korea National Health and Nutrition Examination Survey 2016-2017.Asian biomedicine : research, reviews and news · 2025Article
- Risk factors and renal outcomes of AKI in children with secondary steroid-resistant nephrotic syndrome.Renal failure · 2024Article
- Use of novel structural features to identify urinary biomarkers during acute kidney injury that predict progression to chronic kidney disease.BMC nephrology · 2023Article
- Pediatric Patients Undergoing a Fontan Operation or with a High RACHS-1 Score Require Monitoring for Chronic Kidney Disease in Early Childhood.Pediatric cardiology · 2022Article
- Lower albumin level and longer disease duration are risk factors of acute kidney injury in hospitalized children with nephrotic syndrome.Pediatric nephrology (Berlin, Germany) · 2021Article
- Prognosis of COVID-19 in Patients with Liver and Kidney Diseases: An Early Systematic Review and Meta-Analysis.Tropical medicine and infectious disease · 2020Review
- Causal inference for the effect of environmental chemicals on chronic kidney disease.Computational and structural biotechnology journal · 2020Article
- Ensuring safe drug administration to pediatric patients with renal dysfunction: a multicenter study.Clinical and experimental nephrology · 2018Article
- Quality of life following hospitalization-associated acute kidney injury in children.Journal of nephrology · 2018Article
- Acute kidney injury in idiopathic nephrotic syndrome of childhood is a major risk factor for the development of chronic kidney disease.Renal failure · 2017Article
- Acute kidney injury in premature newborns-definition, etiology, and outcome.Pediatric nephrology (Berlin, Germany) · 2017Article
- Risk of nonsteroidal anti-inflammatory drug-associated renal dysfunction among neonates diagnosed with patent ductus arteriosus and treated with gentamicin.Journal of perinatology : official journal of the California Perinatal Association · 2017Observational
- On the occasion of world kidney day 2017; obesity and its relationship with chronic kidney disease.Journal of nephropathology · 2017Review
- Hypertension in pediatric patients with chronic kidney disease: management challenges.International journal of nephrology and renovascular disease · 2017Review
- Drug-associated acute kidney injury: who's at risk?Pediatric nephrology (Berlin, Germany) · 2017Review
- PROGRESSION OF CHRONIC KIDNEY DISEASE AFTER ACUTE KIDNEY INJURY.Progress in pediatric cardiology · 2016Article
- Longitudinal analysis of serum cystatin C for estimating the glomerular filtration rate in preterm infants.Pediatric nephrology (Berlin, Germany) · 2016Article
- Acute Kidney Injury in Premature, Very Low-Birth-Weight Infants.Journal of pediatric intensive care · 2016Review
Corrections and comments
- Commented on by
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
While emerging evidence indicates that the incidence of both acute kidney injury (AKI) and chronic kidney disease (CKD) in children is rising and that the etiologies are dramatically changing, relatively little is currently known regarding the potential for transition from AKI to CKD. Major barriers to assessing for a potential AKI to CKD link have included lack of a standard pediatric AKI definition, narrow focus only on children with AKI who receive renal replacement therapy, and reliance on serum creatinine as the main biomarker to detect and diagnose AKI and CKD. Recent data have validated a multi-dimensional AKI classification system for children and have suggested chronic kidney sequelae in pediatric populations with AKI or at risk for AKI. In addition, a number of novel AKI biomarkers are being rigorously validated as early indicators of incipient CKD. Our goals for this article are to (1) review the recent changes in pediatric AKI and CKD epidemiology, (2) explore the evidence for a potential AKI to CKD link, and (3) propose new clinical and research paradigms to better elucidate the progression from AKI to CKD.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.