Evidence map›Paper›PMID 20936120›Full record

ReviewClinical & developmental immunology2010

Vaccines and immunotherapeutics for the treatment of malignant disease.

Joel F Aldrich, Devin B Lowe, Michael H Shearer, Richard E Winn, Cynthia A Jumper, Ronald C Kennedy

Open access · goldAbstract readReview
In one paragraph

Review in Clinical & developmental immunology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 39 citations in OpenAlex.

  1. Trial
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Immunological aspects of radiotherapy.Radiation oncology (London, England) · 2014
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Cancer vaccines.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2011
    Article
  13. Article
  14. Article
  15. Metastatic dormancy and progression in thyroid cancer: targeting cells in the metastatic frontier.Thyroid : official journal of the American Thyroid Association · 2011
    Review
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Joel F AldrichDepartment of Microbiology and Immunology, Texas Tech University Health Sciences Center, Lubbock, TX 79430, USA.
Devin B Lowe
Michael H Shearer
Richard E Winn
Cynthia A Jumper
Ronald C Kennedy
Texas Tech University · USTexas Tech University Health Sciences Center · US

Funding

CORE--BABOON RESEARCH RESOURCE PROGRAMP40RR012317 · NCRR · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · PI WHITE, GARY L · 1998 to 2011
$13.0M
NCRR NIH HHS P40 RR012317NCRR NIH HHS RR-12317
6 · The paper itself

Abstract

The employment of the immune system to treat malignant disease represents an active area of biomedical research. The specificity of the immune response and potential for establishing long-term tumor immunity compels researchers to continue investigations into immunotherapeutic approaches for cancer. A number of immunotherapeutic strategies have arisen for the treatment of malignant disease, including various vaccination schemes, cytokine therapy, adoptive cellular therapy, and monoclonal antibody therapy. This paper describes each of these strategies and discusses some of the associated successes and limitations. Emphasis is placed on the integration of techniques to promote optimal scenarios for eliminating cancer.

Indexed as

AnimalsAntibodies, MonoclonalAntigens, NeoplasmCancer VaccinesCytokinesDendritic CellsDogsHumansImmunotherapyMiceNeoplasmsAntibodies, MonoclonalAntigens, NeoplasmCancer VaccinesCytokines

Identifiers

PMID20936120
PMCPMC2948924
OpenAlexW2078974152

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.