ArticleGastroenterology research and practice2010
Toll-like receptor 3 in liver diseases.
Article in Gastroenterology research and practice, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 28 citations in OpenAlex.
- Specific binding sites on Rhesus rotavirus capsid protein dictate the method of endocytosis inducing the murine model of biliary atresia.American journal of physiology. Gastrointestinal and liver physiology · 2024Article
- Effect ofHeliyon · 2024Article
- LIGHT Amplification by NF-Mediators of inflammation · 2023Article
- Knowledge-guided deep learning models of drug toxicity improve interpretation.Patterns (New York, N.Y.) · 2022Article
- Oral administration of PEGylated TLR7 ligand ameliorates alcohol-associated liver disease via the induction of IL-22.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
- Role of γδT cells in liver diseases and its relationship with intestinal microbiota.World journal of gastroenterology · 2020Review
- Toll-like receptor 3 activation increases voluntary alcohol intake in C57BL/6J male mice.Brain, behavior, and immunity · 2019Article
- Association of Toll-Like Receptor 3 and Toll-Like Receptor 9 Single Nucleotide Polymorphisms with Hepatitis C Virus Infection and Hepatic Fibrosis in Egyptian Patients.The American journal of tropical medicine and hygiene · 2017Article
- Association of Toll-Like Receptor 3 Single-Nucleotide Polymorphisms and Hepatitis C Virus Infection.Journal of immunology research · 2017Article
- Toll-like receptors in pathophysiology of liver diseases.World journal of hepatology · 2016Review
- Transglutaminase 2 is dispensable but required for the survival of mice in dextran sulfate sodium-induced colitis.Experimental & molecular medicine · 2016Article
- Commensal microbiota is hepatoprotective and prevents liver fibrosis in mice.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2015Article
- Quiescent hepatic stellate cells functionally contribute to the hepatic innate immune response via TLR3.PloS one · 2014Article
- Toll like receptor 3 plays a critical role in the progression and severity of acetaminophen-induced hepatotoxicity.PloS one · 2013Article
- Toll-like receptors in liver fibrosis: cellular crosstalk and mechanisms.Frontiers in physiology · 2012Article
- The multi-hit hypothesis of primary biliary cirrhosis: polyinosinic-polycytidylic acid (poly I:C) and murine autoimmune cholangitis.Clinical and experimental immunology · 2011Article
- Toll-like receptor signaling in liver regeneration, fibrosis and carcinogenesis.Hepatology research : the official journal of the Japan Society of Hepatology · 2011Article
- Toll-like receptors in secondary obstructive cholangiopathy.Gastroenterology research and practice · 2011Article
- Pathogenesis of Alcohol-Associated Liver Disease.Journal of clinical and experimental hepatologyReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 2 countries.
Funding
Abstract
Toll-like receptor 3 (TLR3) is a member of the TLR family that can recognize double-stranded RNA (dsRNA), playing an important role in antiviral immunity. Recent studies have shown that TLR3 is also expressed on parenchymal and nonparenchymal cells in the liver as well as on several types of immune cells. In this review, we summarize the role of TLR3 in liver injury, inflammation, regeneration, and liver fibrosis, and discuss the implication of TLR3 in the pathogenesis of human liver diseases including viral hepatitis and autoimmune liver disease.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.