Trial reportJournal of substance abuse treatment2011
Bupropion SR and contingency management for adolescent smoking cessation.
Trial report in Journal of substance abuse treatment, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
39 citing papers in PubMed, 5 syntheses or guidelines pooled it, 75 citations in OpenAlex.
- Treatment of Nicotine Use in Adolescents Under 18 Years of Age: An Official American Thoracic Society Clinical Practice Guideline.American journal of respiratory and critical care medicine · 2025Guideline
- Antidepressants for smoking cessation.The Cochrane database of systematic reviews · 2020Pooled it
- Tobacco cessation interventions for young people.The Cochrane database of systematic reviews · 2017Pooled it
- A review of the literature on contingency management in the treatment of substance use disorders, 2009-2014.Preventive medicine · 2016Pooled it
- Antidepressants for smoking cessation.The Cochrane database of systematic reviews · 2014Pooled it
- N-acetylcysteine for youth cannabis use disorder: randomized controlled trial main findings.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2025Trial
- Web-Based Contingency Management for Adolescent Tobacco Smokers: A Clinical Trial.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2020Trial
- Efficacy and Safety of Varenicline for Adolescent Smoking Cessation: A Randomized Clinical Trial.JAMA pediatrics · 2019Trial
- Buspirone treatment of cannabis dependence: A randomized, placebo-controlled trial.Drug and alcohol dependence · 2015Trial
- Achieving cannabis cessation -- evaluating N-acetylcysteine treatment (ACCENT): design and implementation of a multi-site, randomized controlled study in the National Institute on Drug Abuse Clinical Trials Network.Contemporary clinical trials · 2014Trial
- Tobacco cessation treatment for Alaska native adolescents: group randomized pilot trial.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2014Trial
- Internet-based contingency management to promote smoking cessation: a randomized controlled study.Journal of applied behavior analysis · 2013Trial
- An exploratory randomized controlled trial of a novel high-school-based smoking cessation intervention for adolescent smokers using abstinence-contingent incentives and cognitive behavioral therapy.Drug and alcohol dependence · 2013Trial
- Pilot randomized trial of bupropion for adolescent methamphetamine abuse/dependence.The Journal of adolescent health : official publication of the Society for Adolescent Medicine · 2013Trial
- A double-blind randomized controlled trial of N-acetylcysteine in cannabis-dependent adolescents.The American journal of psychiatry · 2012Trial
- Varenicline versus bupropion XL for smoking cessation in older adolescents: a randomized, double-blind pilot trial.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2012Trial
- Effects of contingency management and bupropion on cigarette smoking in smokers with schizophrenia.Psychopharmacology · 2011Trial
- Antidepressants for smoking cessation.The Cochrane database of systematic reviews · 2023Review
- Contingency management and cognitive behavior therapy for smoking cessation among veterans with posttraumatic stress disorder: Design and methodology of a randomized clinical trial.Contemporary clinical trials · 2022Article
- TOBACCO USE DISORDER AND DUAL DISORDERS Joint statement by the Spanish Psychiatry Society and the Spanish Dual Disorders Society.Actas espanolas de psiquiatria · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 1 institution in 1 country.
Funding
Abstract
There is a significant need for evidence-based treatments for adolescent smoking cessation. Prior research, although limited, has suggested potential roles for bupropion sustained-release (SR) and contingency management (CM), but no previous studies have assessed their combined effect. In a double-blind, placebo-controlled design, 134 adolescent smokers were randomized to receive a 6-week course of bupropion SR + CM, bupropion SR + non-CM, placebo + CM, or placebo + non-CM, with final follow-up at 12 weeks. The primary outcome was 7-day cotinine-verified point prevalence abstinence, allowing for a 2-week grace period. Combined bupropion SR + CM treatment yielded significantly superior abstinence rates during active treatment when compared with placebo + non-CM treatment. In addition, combined treatment showed greater efficacy at multiple time points than did either bupropion SR + non-CM or placebo + CM treatment. Combined bupropion SR and CM appears efficacious, at least in the short-term, for adolescent smoking cessation and may be superior to either intervention alone.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.