Evidence map›Paper›PMID 20934212›Full record

ReviewLancet (London, England)2010

Critical care and the global burden of critical illness in adults.

Neill K J Adhikari, Robert A Fowler, Satish Bhagwanjee, Gordon D Rubenfeld

9 registry-linked trialsOpen access · bronzeAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Lancet (London, England), 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 9 registered trials, which are not on this map. Cited by 568 papers, 15 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
568citing papers in PubMed, 15 pooled it
18.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02442102 naterminatednot on this mapstarted 2015, after this paper: background citation

Understanding and Improving Dysphagia After Mechanical Ventilation

TypeinterventionalSponsorJohns Hopkins UniversityRan2015 to 2022Enrolled58ConditionsDeglutition Disorders, Mechanical Ventilation Complication, Complication of Ventilation TherapyArmsExercise and sensory stimulation
NCT03422159 phase2completednot on this mapstarted 2018, after this paper: background citation

Outcomes of Metabolic Resuscitation Using Ascorbic Acid, Thiamine, and Glucocorticoids in the Early Treatment of Sepsis.

TypeinterventionalSponsorCommunity Medical Center, Toms River, NJRan2018 to 2019Enrolled140ConditionsSepsis, Severe, Septic ShockArmsAscorbic Acid, Thiamine, Hydrocortisone, Sodium Chloride 0.9%
NCT03726086 completednot on this mapstarted 2019, after this paper: background citation

Post-extubation Assessment of Laryngeal Symptoms and Severity

TypeobservationalSponsorJohns Hopkins UniversityRan2019 to 2023Enrolled365ConditionsIntubation, Intratracheal, Critical Illness, Mechanical Ventilation Complication, Complication of Ventilation TherapyArmslaryngoscopy
NCT05392010 unknown statusnot on this mapstarted 2022, after this paper: background citation

Assessment of Clinical Practice of Mechanical Ventilation After COVID-19 Pan-demic Among 57 Countries: A Systematic Analysis for the Global BurdEn of Me-chanIcal VeNtilatIon (GEMINI Study) 2022, From VENTILAGROUP.

Typeobservational_patient_registrySponsorHospital Universitario GetafeRan2022 to 2024Enrolled10,900ConditionsMechanical Ventilation, Usual Care, Noninvasive Positive Pressure Ventilation, High Flow Oxygen TherapyArmsno intervention
NCT06051526 completednot on this mapstarted 2023, after this paper: background citation

The African Critical Illness Outcomes Study

TypeobservationalSponsorUniversity of Cape TownRan2023 to 2024Enrolled20,159ConditionsCritical Illness, Mortality
NCT06253325 recruitingnot on this mapstarted 2024, after this paper: background citation

An Observational Pilot Study for the Multi-Modality Risk Prediction and Early Identification of Critically Ill Septic Patients in the Emergency Department

TypeobservationalSponsorUniversity Hospital Southampton NHS Foundation TrustRan2024 to 2025Enrolled60ConditionsSepsisArmsMeasuring tissue oxygenation, Procalcitonin, Mid-regional proadrenomedullin, Hand-held video microscope
NCT06288724 unknown statusnot on this mapstarted 2024, after this paper: background citation

Potentially MOdifiable Factors To ImproVe Outcomes of Mechanically Ventilated Patients in ICUs in a Low-income Country: Rationale and Protocol for a Registry-embedded Prospective Observational Study

Typeobservational_patient_registrySponsorNat Intensive Care Surveillance - MORURan2024 to 2024Enrolled625ConditionsCritical Illness, Invasive Mechanical Ventilation, ICU Mortality, Developing Countries
NCT06531005 unknown statusnot on this mapstarted 2024, after this paper: background citation

Assessment of Ventilation Parameters for Extubation Prediction in ICU

TypeobservationalSponsorAnkara UniversityRan2024 to 2025Enrolled100ConditionsAcute Respiratory Failure, Invasive Mechanical Ventilation
NCT06532994 recruitingnot on this mapstarted 2024, after this paper: background citation

Development and Validation of a Prediction Algorithms to Estimate the Clinical Effect of Early Rehabilitation on ICU Survivors Received Mechanical Ventilation in the ICU

TypeobservationalSponsorWuhan UniversityRan2024 to 2026Enrolled250ConditionsIntensive Care, Mechanical Ventilation, Rehabilitation, AlgorithmsArmsEarly rehabilitation intervention
3 · Its place in the literature

Who cites it

568 citing papers in PubMed, 15 syntheses or guidelines pooled it, 1,334 citations in OpenAlex.

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  12. Noninvasive respiratory support after extubation: a systematic review and network meta-analysis.European respiratory review : an official journal of the European Respiratory Society · 2023
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508 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 2 countries.

Neill K J AdhikariInterdepartmental Division of Critical Care, University of Toronto and Department of Critical Care Medicine, Sunnybrook Health Sciences Centre, Toronto, ON, Canada.
Robert A Fowler
Satish Bhagwanjee
Gordon D Rubenfeld
Health Sciences Centre · CASunnybrook Health Science Centre · CAUniversity of Toronto · CAUniversity of Washington · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Critical care has evolved from treatment of poliomyelitis victims with respiratory failure in an intensive care unit to treatment of severely ill patients irrespective of location or specific technology. Population-based studies in the developed world suggest that the burden of critical illness is higher than generally appreciated and will increase as the population ages. Critical care capacity has long been needed in the developing world, and efforts to improve the care of the critically ill in these settings are starting to occur. Expansion of critical care to handle the consequences of an ageing population, natural disasters, conflict, inadequate primary care, and higher-risk medical therapies will be challenged by high costs at a time of economic constraint. To meet this challenge, investigators in this discipline will need to measure the global burden of critical illness and available critical-care resources, and develop both preventive and therapeutic interventions that are generalisable across countries.

Indexed as

Critical CareGlobal HealthAdultCritical IllnessDeveloped CountriesDeveloping CountriesDisastersDisease OutbreaksHumansIntensive Care UnitsMedicinePopulation DynamicsPrognosis

Identifiers

PMID20934212
PMCPMC7136988
OpenAlexW2029396930

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

and 3 more above

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.