ReviewCurrent opinion in immunology2010
Interface between hemostasis and adaptive immunity.
Review in Current opinion in immunology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed.
- An Ixodes persulcatus Inhibitor of Plasmin and Thrombin Hinders Keratinocyte Migration, Blood Coagulation, and Endothelial Permeability.The Journal of investigative dermatology · 2024Article
- Review
- Immunomodulation of Skin Repair: Cell-Based Therapeutic Strategies for Skin Replacement (A Comprehensive Review).Biomedicines · 2022Review
- The impact of platelets on pulmonary microcirculation throughout COVID-19 and its persistent activating factors.Frontiers in immunology · 2022Review
- Association of TyG Index with CT Features in Patients with Tuberculosis and Diabetes Mellitus.Infection and drug resistance · 2022Article
- Characterizing Patients with Recurrent Urinary Tract Infections in Vesicoureteral Reflux: A Pilot Study of the Urinary Proteome.Molecular & cellular proteomics : MCP · 2020Article
- Extracellular Matrix-Based Strategies for Immunomodulatory Biomaterials Engineering.Advanced healthcare materials · 2019Review
- Platelets in Pulmonary Immune Responses and Inflammatory Lung Diseases.Physiological reviews · 2016Review
- In situ regeneration of bioactive coatings enabled by an evolved Staphylococcus aureus sortase A.Nature communications · 2016Article
- New frontiers for platelet CD154.Experimental hematology & oncology · 2015Article
- Immobilization of actively thromboresistant assemblies on sterile blood-contacting surfaces.Advanced healthcare materials · 2014Article
- Influence of mental stress on platelet bioactivity.World journal of psychiatry · 2012Review
- Assembly of the prothrombinase complex on the surface of human foreskin fibroblasts: Implications for connective tissue growth factor.Thrombosis research · 2012Article
- A biologically active surface enzyme assembly that attenuates thrombus formation.Advanced functional materials · 2011Article
- Role of T lymphocytes in angiotensin II-mediated microvascular thrombosis.Hypertension (Dallas, Tex. : 1979) · 2011Article
- Historical perspective and future directions in platelet research.Journal of thrombosis and haemostasis : JTH · 2011Review
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Stress induced activation or denudation of the endothelium elicits arrest and activation of platelets with attendant triggering of coagulation, culminating in a physical barrier to limit blood loss. Recently, coagulation-activated osteopontin, chemerin, and protease-activated receptor signaling, as well as platelet-derived molecules including platelet factor 4, serotonin, P-selectin, and CD154 (CD40L) have been revealed as new links between hemostasis and adaptive immunity. The initiation of hemostasis establishes a local state of inflammation that serves as an adjuvant system for antigen presentation, consequently influencing the onset and functional characteristics of an evolving adaptive immune response. In this context, the hemostatic system and its associated signaling pathways warrant further study as novel therapeutic targets that may enhance, abrogate, or otherwise selectively direct the adaptive immune response.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.