Evidence map›Paper›PMID 20932583›Full record

Trial reportOphthalmology2011

Treatment outcomes in the Ahmed Baerveldt Comparison Study after 1 year of follow-up.

Donald L Budenz, Keith Barton, William J Feuer, Joyce Schiffman, Vital P Costa, David G Godfrey, Yvonne M Buys, Ahmed Baerveldt Comparison Study Group

Registry-linked trialAbstract readComparative StudyMulticenter StudyRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Ophthalmology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00376363 (Ahmed Versus Baerveldt Comparison Study), which is not on this map. Cited by 116 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
116citing papers in PubMed, 8 pooled it
10.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00376363 nacompletednot on this map

Ahmed Versus Baerveldt Comparison Study

TypeinterventionalSponsorUniversity of MiamiRan2005 to 2014Enrolled276ConditionsGlaucomaArmsAhmed implant, Baerveldt implant
3 · Its place in the literature

Who cites it

116 citing papers in PubMed, 8 syntheses or guidelines pooled it, 284 citations in OpenAlex.

  1. Pooled it
  2. Efficacy of glaucoma drainage devices in uveitic glaucoma and a meta-analysis of the literature.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2019
    Pooled it
  3. Aqueous shunts for glaucoma.The Cochrane database of systematic reviews · 2017
    Pooled it
  4. Pooled it
  5. Pooled it
  6. Pooled it
  7. Pooled it
  8. Pooled it
  9. Trial
  10. Trial
  11. Trial
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  13. [Ahmed glaucoma valve via pars plana access. Long-term results of implantation for therapy refractive glaucoma].Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft · 2013
    Trial
  14. Trial
  15. Trial
  16. Trial
  17. Article
  18. Two-year efficacy and safety outcomes of the Paul Glaucoma Implant compared to the Ahmed Glaucoma Valve.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026
    Article
  19. Tube obstruction caused by blood clots following PreserFlo MicroShunt surgery.American journal of ophthalmology case reports · 2026
    Article
  20. Article

56 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 4 countries.

Donald L BudenzDepartment of Ophthalmology, Bascom Palmer Eye Institute, Miller School of Medicine, University of Miami, Miami, FL 33136, USA.
Keith Barton
William J Feuer
Joyce Schiffman
Vital P Costa
David G Godfrey
Yvonne M Buys
Ahmed Baerveldt Comparison Study Group
University of Miami · USGlaucoma Associates of Texas · USUniversidade Estadual de Campinas (UNICAMP) · BRUniversity College London · GBUniversity of Toronto · CA

Funding

Shared Equipment ModuleP30EY014801 · NEI · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI Dmitry V Ivanov · 2004 to 2026
$12.2M
NEI NIH HHS P30 EY014801
6 · The paper itself

Abstract

purposeTo determine the relative efficacy and complications of the Ahmed glaucoma valve (AGV) model FP7 (New World Medical, Ranchos Cucamonga, CA) and the Baerveldt glaucoma implant (BGI) model 101-350 (Abbott Medical Optics, Abbott Park, IL) in refractory glaucoma.

designMulticenter, randomized, controlled clinical trial.

participantsTwo hundred seventy-six patients, including 143 in the AGV group and 133 in the BGI group.

methodsPatients 18 to 85 years of age with refractory glaucoma having intraocular pressure (IOP) of 18 mmHg or more in whom an aqueous shunt was planned were randomized to undergo implantation of either an AGV or a BGI.

main outcome measuresThe primary outcome was failure, defined as IOP >21 mmHg or not reduced by 20% from baseline, IOP ≤5 mmHg, reoperation for glaucoma or removal of implant, or loss of light perception vision. Secondary outcomes included mean IOP, visual acuity, use of supplemental medical therapy, and complications.

resultsPreoperative IOP (mean±standard deviation [SD]) was 31.2±11.2 mmHg in the AGV group and 31.8±12.5 mmHg in the BGI group (P = 0.71). At 1 year, mean±SD IOP was 15.4±5.5 mmHg in the AGV group and 13.2±6.8 mmHg in the BGI group (P = 0.007). The mean±SD number of glaucoma medications was 1.8±1.3 in the AGV group and 1.5±1.4 in the BGI group (P = 0.071). The cumulative probability of failure was 16.4% (standard error [SE], 3.1%) in the AGV group and 14.0% (SE, 3.1%) in the BGI group at 1 year (P = 0.52). More patients experienced early postoperative complications in the BGI group (n = 77; 58%) compared with the AGV group (n = 61; 43%; P = 0.016). Serious postoperative complications associated with reoperation, vision loss of ≥2 Snellen lines, or both occurred in 29 patients (20%) in the AGV group and in 45 patients (34%) in the BGI group (P = 0.014).

conclusionsAlthough the average IOP after 1 year was slightly higher in patients who received an AGV, there were fewer early and serious postoperative complications associated with the use of the AGV than the BGI.

Indexed as

Glaucoma Drainage ImplantsProsthesis ImplantationAdolescentAdultAgedAged, 80 and overDevice RemovalFemaleFollow-Up StudiesGlaucomaHumansIntraocular PressureIntraoperative ComplicationsMaleMiddle AgedPostoperative Complications

Identifiers

PMID20932583
PMCPMC3020266
OpenAlexW2038333013

What OpenQuestion holds

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LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.