Evidence map›Paper›PMID 20931295›Full record

ArticleImmunologic research2011

On the logic of restrictive recognition of peptide by the T-cell antigen receptor.

Melvin Cohn

Abstract read
In one paragraph

Article in Immunologic research, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Melvin CohnConceptual Immunology Group, The Salk Institute For Biological Studies, La Jolla, CA 92037, USA. cohn@salk.edu

Funding

EVOLUTIONARY MODELS OF THE IMMUNE SYSTEMR01RR007716 · NCRR · SALK INSTITUTE FOR BIOLOGICAL STUDIES · PI COHN, MELVIN · 1991 to 2010
$4.5M
NCRR NIH HHS R01 RR007716NCRR NIH HHS RR07716
6 · The paper itself

Abstract

This essay provides an analysis of the inadequacy of the current view of restrictive recognition of peptide by the T-cell antigen receptor. A competing model is developed, and the experimental evidence for the prevailing model is reinterpreted in the new framework. The goal is to contrast the two models with respect to their consistency, coverage of the data, explanatory power, and predictability.

Indexed as

AnimalsHumansModels, ImmunologicalPeptidesReceptors, Antigen, T-CellStructure-Activity RelationshipPeptidesReceptors, Antigen, T-Cell

Identifiers

PMID20931295
PMCPMC3085606

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.