ArticleNature2010
Functional connectivity in the retina at the resolution of photoreceptors.
Article in Nature, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 171 papers.
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Who cites it
171 citing papers in PubMed.
- Synaptic Organization of the Primate Retina: Toward a Human Foveal Connectome.Annual review of vision science · 2026Review
- Approaching a connectome of the human foveal retina.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- An image-computable spatio-chromatic receptive field model of the midget retinal ganglion cell mosaic across the retina.Journal of computational neuroscience · 2026Article
- Physiological basis of resolution acuity in vision.Nature communications · 2026Article
- Connectome of a human foveal retina.bioRxiv : the preprint server for biology · 2026Article
- Amacrine cell inputs to OFF midget ganglion cells in macaque retina.The Journal of physiology · 2025Article
- Local variations in L/M ratio influence the detection and color naming of small spots.Journal of vision · 2025Article
- Chromatic and achromatic contrast sensitivity in the far periphery.Journal of vision · 2025Article
- Local variations in L/M ratio influence the detection and color naming of small spots.bioRxiv : the preprint server for biology · 2025Article
- Decomposition of retinal ganglion cell electrical images for cell type and functional inference.bioRxiv : the preprint server for biology · 2025Article
- A standardized nomenclature for the rods and cones of the vertebrate retina.PLoS biology · 2025Article
- Morphology and connectivity of retinal horizontal cells in two avian species.Frontiers in cellular neuroscience · 2025Article
- Review
- Electroretinographic responses to periodic stimuli in primates and the relevance for visual perception and for clinical studies.Visual neuroscience · 2024Review
- Fixational eye movements enhance the precision of visual information transmitted by the primate retina.Nature communications · 2024Article
- A circuit motif for color in the human foveal retina.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Fixational Eye Movements Enhance the Precision of Visual Information Transmitted by the Primate Retina.bioRxiv : the preprint server for biology · 2024Article
- Unique yellow shifts for small and brief stimuli in the central retina.Journal of vision · 2024Article
- Article
- The vertebrate retina: a window into the evolution of computation in the brain.Current opinion in behavioral sciences · 2024Review
111 more citing papers are in PubMed but not listed here.
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Authors and funding
13 authors.
Funding
Abstract
To understand a neural circuit requires knowledge of its connectivity. Here we report measurements of functional connectivity between the input and ouput layers of the macaque retina at single-cell resolution and the implications of these for colour vision. Multi-electrode technology was used to record simultaneously from complete populations of the retinal ganglion cell types (midget, parasol and small bistratified) that transmit high-resolution visual signals to the brain. Fine-grained visual stimulation was used to identify the location, type and strength of the functional input of each cone photoreceptor to each ganglion cell. The populations of ON and OFF midget and parasol cells each sampled the complete population of long- and middle-wavelength-sensitive cones. However, only OFF midget cells frequently received strong input from short-wavelength-sensitive cones. ON and OFF midget cells showed a small non-random tendency to selectively sample from either long- or middle-wavelength-sensitive cones to a degree not explained by clumping in the cone mosaic. These measurements reveal computations in a neural circuit at the elementary resolution of individual neurons.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.