Evidence map›Paper›PMID 20929875›Full record

ArticleNucleic acids research2011

The IKMC web portal: a central point of entry to data and resources from the International Knockout Mouse Consortium.

Martin Ringwald, Vivek Iyer, Jeremy C Mason, Kevin R Stone, Hamsa D Tadepally, James A Kadin, Carol J Bult, Janan T Eppig, Darren J Oakley, Sebastien Briois and 8 more

Abstract read
In one paragraph

Article in Nucleic acids research, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers.

0numbers the graph read from it
0cells of the map it votes in
62citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

62 citing papers in PubMed.

  1. Article
  2. A simple method for repeated in vivo sperm collection from laboratory mice.Journal of assisted reproduction and genetics · 2024
    Article
  3. Review
  4. Article
  5. Viral Vector-Induced Ocular Hypertension in Mice.Methods in molecular biology (Clifton, N.J.) · 2023
    Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Accessing Data Resources in the Mouse Phenome Database for Genetic Analysis of Murine Life Span and Health Span.The journals of gerontology. Series A, Biological sciences and medical sciences · 2016
    Article
  16. Genome Wide Conditional Mouse Knockout Resources.Drug discovery today. Disease models · 2016
    Article
  17. Article
  18. A mouse informatics platform for phenotypic and translational discovery.Mammalian genome : official journal of the International Mammalian Genome Society · 2015
    Article
  19. Collaborative Cross and Diversity Outbred data resources in the Mouse Phenome Database.Mammalian genome : official journal of the International Mammalian Genome Society · 2015
    Article
  20. Beyond knockouts: the International Knockout Mouse Consortium delivers modular and evolving tools for investigating mammalian genes.Mammalian genome : official journal of the International Mammalian Genome Society · 2015
    Article

2 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Martin RingwaldThe Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609, USA. ringwald@informatics.jax.org
Vivek Iyer
Jeremy C Mason
Kevin R Stone
Hamsa D Tadepally
James A Kadin
Carol J Bult
Janan T Eppig
Darren J Oakley
Sebastien Briois
Elia Stupka
Vincenza Maselli
Damian Smedley
Songyan Liu
Jens Hansen
Richard Baldock
Geoff G Hicks
William C Skarnes

Funding

Data Coordination Center for the Knockout Mouse Project (KOMP)U01HG004074 · NHGRI · JACKSON LABORATORY · PI RINGWALD, MARTIN · 2006 to 2010
$1.6M
Medical Research Council MC_U127527203NHGRI NIH HHS HG004074
6 · The paper itself

Abstract

The International Knockout Mouse Consortium (IKMC) aims to mutate all protein-coding genes in the mouse using a combination of gene targeting and gene trapping in mouse embryonic stem (ES) cells and to make the generated resources readily available to the research community. The IKMC database and web portal (www.knockoutmouse.org) serves as the central public web site for IKMC data and facilitates the coordination and prioritization of work within the consortium. Researchers can access up-to-date information on IKMC knockout vectors, ES cells and mice for specific genes, and follow links to the respective repositories from which corresponding IKMC products can be ordered. Researchers can also use the web site to nominate genes for targeting, or to indicate that targeting of a gene should receive high priority. The IKMC database provides data to, and features extensive interconnections with, other community databases.

Indexed as

Databases, GeneticMice, KnockoutAllelesAnimalsGene TargetingGenetic VectorsGenomicsInternetMiceMolecular Sequence AnnotationUser-Computer Interface

Identifiers

PMID20929875
PMCPMC3013768

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.