ArticleJournal of nanobiotechnology2010
The impact of CdSe/ZnS Quantum Dots in cells of Medicago sativa in suspension culture.
Article in Journal of nanobiotechnology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Meta-analysis of cellular toxicity for cadmium-containing quantum dots.Nature nanotechnology · 2016Pooled it
- Enhancing lettuce yield via Cu/Fe-layered double hydroxide nanoparticles spraying.Journal of nanobiotechnology · 2023Article
- Sulfur deficiency mediated visible emission of ZnS QDs by magnesium dopant and their application in waste water treatment.Heliyon · 2023Article
- Examining the uptake and bioaccumulation of molybdenum nanoparticles and their effect on antioxidant activities in growing rice seedlings.Environmental science and pollution research international · 2021Article
- Advantage of Nanotechnology-Based Genome Editing System and Its Application in Crop Improvement.Frontiers in plant science · 2021Review
- Nitric oxide and ROS mediate autophagy and regulate Alternaria alternata toxin-induced cell death in tobacco BY-2 cells.Scientific reports · 2019Article
- Mycorrhizal Fungi Respond to Resource Inequality by Moving Phosphorus from Rich to Poor Patches across Networks.Current biology : CB · 2019Article
- Biochemical synthesis of gold nanoparticles from leaf protein ofIET nanobiotechnology · 2019Article
- Evaluating the Toxic Impacts of Cadmium Selenide Nanoparticles on the Aquatic Plant Lemna minor.Molecules (Basel, Switzerland) · 2019Article
- Nanotechnology in Plant Science: To Make a Long Story Short.Frontiers in bioengineering and biotechnology · 2019Review
- Flavonoids and darkness lower PCD in senescing Vitis vinifera suspension cell cultures.BMC plant biology · 2016Article
- CdSe/ZnS quantum dots trigger DNA repair and antioxidant enzyme systems in Medicago sativa cells in suspension culture.BMC biotechnology · 2013Article
- Determination of a threshold dose to reduce or eliminate CdTe-induced toxicity in L929 cells by controlling the exposure dose.PloS one · 2013Article
- Multiwalled carbon nanotubes in alfalfa and wheat: toxicology and uptake.Journal of the Royal Society, Interface · 2012Article
- Quantum dots: synthesis, bioapplications, and toxicity.Nanoscale research letters · 2012Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundNanotechnology has the potential to provide agriculture with new tools that may be used in the rapid detection and molecular treatment of diseases and enhancement of plant ability to absorb nutrients, among others. Data on nanoparticle toxicity in plants is largely heterogeneous with a diversity of physicochemical parameters reported, which difficult generalizations. Here a cell biology approach was used to evaluate the impact of Quantum Dots (QDs) nanocrystals on plant cells, including their effect on cell growth, cell viability, oxidative stress and ROS accumulation, besides their cytomobility.
resultsA plant cell suspension culture of Medicago sativa was settled for the assessment of the impact of the addition of mercaptopropanoic acid coated CdSe/ZnS QDs. Cell growth was significantly reduced when 100 mM of mercaptopropanoic acid -QDs was added during the exponential growth phase, with less than 50% of the cells viable 72 hours after mercaptopropanoic acid -QDs addition. They were up taken by Medicago sativa cells and accumulated in the cytoplasm and nucleus as revealed by optical thin confocal imaging. As part of the cellular response to internalization, Medicago sativa cells were found to increase the production of Reactive Oxygen Species (ROS) in a dose and time dependent manner. Using the fluorescent dye H2DCFDA it was observable that mercaptopropanoic acid-QDs concentrations between 5-180 nM led to a progressive and linear increase of ROS accumulation.
conclusionsOur results showed that the extent of mercaptopropanoic acid coated CdSe/ZnS QDs cytotoxicity in plant cells is dependent upon a number of factors including QDs properties, dose and the environmental conditions of administration and that, for Medicago sativa cells, a safe range of 1-5 nM should not be exceeded for biological applications.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.