ArticleParticle and fibre toxicology2010
Changes in deceleration capacity of heart rate and heart rate variability induced by ambient air pollution in individuals with coronary artery disease.
Article in Particle and fibre toxicology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
39 citing papers in PubMed, 4 syntheses or guidelines pooled it, 96 citations in OpenAlex.
- Acute effect of ambient fine particulate matter on heart rate variability: an updated systematic review and meta-analysis of panel studies.Environmental health and preventive medicine · 2020Pooled it
- A systematic review of cardiovascular responses associated with ambient black carbon and fine particulate matter.Environment international · 2019Pooled it
- Systematic review of the effects of black carbon on cardiovascular disease among individuals with pre-existing disease.International journal of public health · 2013Pooled it
- An epidemiological appraisal of the association between heart rate variability and particulate air pollution: a meta-analysis.Heart (British Cardiac Society) · 2012Pooled it
- Traffic-related air pollution and acute changes in heart rate variability and respiratory function in urban cyclists.Environmental health perspectives · 2011Trial
- Analysis of clinical and heart rate variability parameters associated with single-vessel and multivessel coronary artery disease: A retrospective study.Pakistan journal of medical sciences · 2026Article
- Short-term association between ambient air pollution and heart rate variability: results from the population-based KORA S4 and FF4 studies.Particle and fibre toxicology · 2025Article
- Enhancing Comprehensive Assessments in Chronic Heart Failure Caused by Ischemic Heart Disease: The Diagnostic Utility of Holter ECG Parameters.Medicina (Kaunas, Lithuania) · 2024Article
- Short-term exposure to ultrafine and fine particulate matter with multipollutant modelling on heart rate variability among seniors and children from the CorPuScula (coronary, pulmonary, sanguis) longitudinal study in Germany.Frontiers in epidemiology · 2023Article
- Identification of Lignan Compounds as New 6-Phosphogluconate Dehydrogenase Inhibitors for Lung Cancer.Metabolites · 2022Article
- Personal exposure to particulate matter and heart rate variability among informal electronic waste workers at Agbogbloshie: a longitudinal study.BMC public health · 2021Article
- Response of the Cardiac Autonomic Control to Exposure to Nanoparticles and Noise: A Cross-Sectional Study of Airport Ground Staff.International journal of environmental research and public health · 2021Article
- Association of Long-Term Air Pollution with Prevalence and Incidence of Distal Sensorimotor Polyneuropathy: KORA F4/FF4 Study.Environmental health perspectives · 2020Article
- Silica nanoparticles induce unfolded protein reaction mediated apoptosis in spermatocyte cells.Toxicology research · 2020Article
- Geometric indexes of heart rate variability in healthy individuals exposed to long-term air pollution.Environmental science and pollution research international · 2020Article
- Ambient and controlled exposures to particulate air pollution and acute changes in heart rate variability and repolarization.Scientific reports · 2019Article
- Short-term effects of fine particulate matter and ozone on the cardiac conduction system in patients undergoing cardiac catheterization.Particle and fibre toxicology · 2018Article
- Application of linear mixed-effects model with LASSO to identify metal components associated with cardiac autonomic responses among welders: a repeated measures study.Occupational and environmental medicine · 2017Article
- In vitro toxicoproteomic analysis of A549 human lung epithelial cells exposed to urban air particulate matter and its water-soluble and insoluble fractions.Particle and fibre toxicology · 2017Article
- Associations of PMInternational journal of environmental research and public health · 2017Article
Corrections and comments
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Authors and funding
14 authors at 6 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
objectiveExposure to ambient particles has been shown to be responsible for cardiovascular effects, especially in elderly with cardiovascular disease. The study assessed the association between deceleration capacity (DC) as well as heart rate variability (HRV) and ambient particulate matter (PM) in patients with coronary artery disease (CAD).
methodsA prospective study with up to 12 repeated measurements was conducted in Erfurt, Germany, between October 2000 and April 2001 in 56 patients with physician-diagnosed ischemic heart disease, stable angina pectoris or prior myocardial infarction at an age of at least 50 years. Twenty-minute ECG recordings were obtained every two weeks and 24-hour ECG recordings every four weeks. Exposure to PM (size range from 10 nm to 2.5 μm), and elemental (EC) and organic (OC) carbon was measured. Additive mixed models were used to analyze the association between PM and ECG recordings.
resultsThe short-term recordings showed decrements in the high-frequency component of HRV as well as in RMSSD (root-mean-square of successive differences of NN intervals) in association with increments in EC and OC 0-23 hours prior to the recordings. The long-term recordings revealed decreased RMSSD and pNN50 (% of adjacent NN intervals that differed more than 50 ms) in association with EC and OC 24-47 hours prior to the recordings. In addition, highly significant effects were found for DC which decreased in association with PM2.5, EC and OC concurrent with the ECG recordings as well as with a lag of up to 47 hours.
conclusionsThe analysis showed significant effects of ambient particulate air pollution on DC and HRV parameters reflecting parasympathetic modulation of the heart in patients with CAD. An air pollution-related decrease in parasympathetic tone as well as impaired heart rate deceleration capacity may contribute to an increased risk for cardiac morbidity and sudden cardiac death in vulnerable populations.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.