ArticleCurrent microbiology2011
Curing the plasmid pXO2 from Bacillus anthracis A16 using plasmid incompatibility.
Article in Current microbiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- A predatory gene drive for targeted control of self-transmissible plasmids.Science advances · 2025Article
- Rapid detection assays for Bacillus anthracis, Yersinia pestis, and Brucella spp. via triplex-recombinase polymerase amplification.Molecular biology reports · 2025Article
- Effect of Nk-lysin peptides on bacterial growth, MIC, antimicrobial resistance, and viral activities.Animal biotechnology · 2024Article
- A CRISPR/Cas12a-based DNAzyme visualization system for rapid, non-electrically dependent detection ofEmerging microbes & infections · 2022Article
- Application of CRISPR/Cas9 System for Plasmid Elimination and Bacterial Killing ofFrontiers in microbiology · 2021Article
- Targeting Plasmids to Limit Acquisition and Transmission of Antimicrobial Resistance.Frontiers in microbiology · 2020Review
- Highly Efficient Genome Engineering inFrontiers in microbiology · 2019Article
- Strategies to combat antimicrobial resistance: anti-plasmid and plasmid curing.FEMS microbiology reviews · 2018Review
- Article
- Ecology and evolution as targets: the need for novel eco-evo drugs and strategies to fight antibiotic resistance.Antimicrobial agents and chemotherapy · 2011Review
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Plasmid incompatibility, which has no effect on other plasmids or chromosomal genes, can be used to cure a target plasmid. In this report, we successfully cured the plasmid pXO2 from Bacillus anthracis A16 with a newly constructed, incompatible plasmid pKSV7-oriIV and obtained a new pXO2-cured strain, designated A16PI2. This is the first time that a plasmid was cured from the B. anthracis wild-type strain A16 utilizing this principle, which could be considered as an efficacious method to cure large plasmids.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.