Evidence map›Paper›PMID 20927288›Full record

ArticleJournal of global infectious diseases2010

Quinolone and cephalosporin resistance in enteric Fever.

Malini Rajinder Capoor, Deepthi Nair

Open access · goldAbstract read
In one paragraph

Article in Journal of global infectious diseases, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
2.9field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 48 citations in OpenAlex.

  1. A Systematic Review on Antimicrobial Resistance amongThe American journal of tropical medicine and hygiene · 2020
    Pooled it
  2. Article
  3. Infectious disorders drug targets · 2024
    Review
  4. Frontiers in microbiology · 2023
    Article
  5. Integron-Associated Antibiotic Resistance inArchives of Razi Institute · 2022
    Article
  6. Article
  7. Longitudinal Typhoid Fever Trends in India from 2000 to 2015.The American journal of tropical medicine and hygiene · 2018
    Article
  8. Review
  9. Global increase and geographic convergence in antibiotic consumption between 2000 and 2015.Proceedings of the National Academy of Sciences of the United States of America · 2018
    Article
  10. Investigation into a community outbreak ofThe Indian journal of medical research · 2017
    Article
  11. Drug Resistance Pattern in the Recent Isolates ofJournal of clinical and diagnostic research : JCDR · 2017
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Global fluoroquinolone resistance epidemiology and implictions for clinical use.Interdisciplinary perspectives on infectious diseases · 2012
    Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Malini Rajinder CapoorDepartment of Microbiology, Vardhman Mahaveer Medical College and Safdarjung Hospital, New Delhi, India.
Deepthi Nair
Vardhman Mahavir Medical College & Safdarjung Hospital · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Enteric fever is a major public health problem in developing countries. Ciprofloxacin resistance has now become a norm in the Indian subcontinent. Novel molecular substitutions may become frequent in future owing to selective pressures exerted by the irrational use of ciprofloxacin in human and veterinary therapeutics, in a population endemic with nalidixic acid-resistant strains. The therapeutics of ciprofloxacin-resistant enteric fever narrows down to third- and fourth-generation cephalosporins, azithromycin, tigecycline and penems. The first-line antimicrobials ampicillin, chloramphenicol and co-trimoxazole need to be rolled back. Antimicrobial surveillance coupled with molecular analysis of fluoroquinolone resistance is warranted for reconfirming novel and established molecular patterns for therapeutic reappraisal and for novel-drug targets. This review explores the antimicrobial resistance and its molecular mechanisms, as well as novel drugs in the therapy of enteric fever.

Indexed as

AzithromycinCiprofloxacin resistanceEnteric feverMolecular targetsPenemsTigecycline

Identifiers

PMID20927288
PMCPMC2946683
OpenAlexW2018796539

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.