Evidence map›Paper›PMID 20927191›Full record

ReviewPLoS neglected tropical diseases2010

Mycobacterium africanum--review of an important cause of human tuberculosis in West Africa.

Bouke C de Jong, Martin Antonio, Sebastien Gagneux

Registry-linked trialOpen access · goldAbstract readReview
In one paragraph

Review in PLoS neglected tropical diseases, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02744469 (Implications of the Population Structure of the Mycobacterium Tuberculosis Complex in Benin for Tuberculosis Presentation, Diagnosis and Outcome), which is not on this map. Cited by 149 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
149citing papers in PubMed, 2 pooled it
6.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02744469 completednot on this mapstarted 2016, after this paper: background citation

Implications of the Population Structure of the Mycobacterium Tuberculosis Complex in Benin for Tuberculosis Presentation, Diagnosis and Outcome

TypeobservationalSponsorLaboratoire de Référence des MycobactériesRan2016 to 2019Enrolled1,490ConditionsTuberculosisArmsNo intervention (observational study)
3 · Its place in the literature

Who cites it

149 citing papers in PubMed, 2 syntheses or guidelines pooled it, 314 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
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  10. Pathogens (Basel, Switzerland) · 2025
    Review
  11. TheeLife · 2025
    Article
  12. Review
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  14. Loss of theScience advances · 2025
    Article
  15. Article
  16. Decoding EcuadorianBiomedicines · 2025
    Article
  17. Article
  18. Article
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  20. Article

89 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 4 countries.

Bouke C de JongMRC Laboratories, Bacterial Diseases Programme, Fajara, The Gambia. bdejong@itg.be
Martin Antonio
Sebastien Gagneux
Instituut voor Tropische Geneeskunde · BEMRC Unit the Gambia · GMSwiss Tropical and Public Health Institute · CH

Funding

POPULATION-BASED MOLECULAR EPIDEMIOLOGY OF TUBERCULOSISR01AI034238 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI HOPEWELL, PHILIP C · 1993 to 2010
$9.3M
Mycobacterial Determinants of Cavitation &TransmissionK01TW006083 · FIC · STANFORD UNIVERSITY · PI DE JONG, BOUKE C · 2002 to 2010
$780k
FIC NIH HHS 05TW006083FIC NIH HHS K01 TW006083Medical Research Council MC_U117588500Medical Research Council MC_U190074190Medical Research Council MC_U190081982Medical Research Council MC_U190081991NIAID NIH HHS AI034238NIAID NIH HHS R01 AI034238PHS HHS HHSN266200700022C
6 · The paper itself

Abstract

Mycobacterium africanum consists of two phylogenetically distinct lineages within the Mycobacterium tuberculosis complex, known as M. africanum West African 1 and M. africanum West African 2. These lineages are restricted to West Africa, where they cause up to half of human pulmonary tuberculosis. In this review we discuss the definition of M. africanum, describe the prevalence and restricted geographical distribution of M. africanum West African 1 and 2, review the occurrence of M. africanum in animals, and summarize the phenotypic differences described thus far between M. africanum and M. tuberculosis sensu stricto.

Indexed as

Africa, WesternAnimalsGeographyHumansMycobacterium tuberculosisPhylogenyPrevalenceTuberculosis, Pulmonary

Identifiers

PMID20927191
PMCPMC2946903
OpenAlexW2147353041

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.