Evidence map›Paper›PMID 20923974›Full record

ArticleGenetics2010

Cdc14-dependent dephosphorylation of a kinetochore protein prior to anaphase in Saccharomyces cerevisiae.

Bungo Akiyoshi, Sue Biggins

Abstract read
In one paragraph

Article in Genetics, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Analog-sensitive Cdk1 as a tool to study mitotic exit: protein phosphatase 1 is required downstream from Cdk1 inactivation in budding yeast.Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology · 2023
    Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. The Multiple Roles of the Cdc14 Phosphatase in Cell Cycle Control.International journal of molecular sciences · 2020
    Review
  7. Article
  8. Review
  9. Synthetic physical interactions map kinetochore regulators and regions sensitive to constitutive Cdc14 localization.Proceedings of the National Academy of Sciences of the United States of America · 2015
    Article
  10. Article
  11. Cell cycle-specific cleavage of Scc2 regulates its cohesin deposition activity.Proceedings of the National Academy of Sciences of the United States of America · 2014
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Bungo AkiyoshiFred Hutchinson Cancer Research Center, Molecular and Cellular Biology Program, University of Washington, Seattle, Washington 98195, USA.
Sue Biggins

Funding

Regulation of Chromosome SegregationR01GM064386 · NIGMS · FRED HUTCHINSON CANCER RESEARCH CENTER · PI BIGGINS, SUSAN · 2002 to 2022
$7.2M
Regulation of Centromeric ChromatinR01GM078069 · NIGMS · FRED HUTCHINSON CANCER RESEARCH CENTER · PI BIGGINS, SUSAN · 2007 to 2015
$2.7M
NIGMS NIH HHS GM064386NIGMS NIH HHS GM078069NIGMS NIH HHS R01 GM064386NIGMS NIH HHS R01 GM078069
6 · The paper itself

Abstract

The budding yeast Cdc14 phosphatase reverses Cdk1 phosphorylation to promote mitotic exit. Although Cdc14 activity is thought to be restricted to anaphase, we found that dephosphorylation of the Dsn1 kinetochore protein in metaphase requires Cdc14. These data suggest that there is a nonnucleolar pool of active Cdc14 prior to anaphase.

Indexed as

AnaphaseCDC2 Protein KinaseCell Cycle ProteinsChromosomal Proteins, Non-HistoneKinetochoresMitosisPhosphorylationProtein Tyrosine PhosphatasesSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsCDC14 protein, S cerevisiaeCDC2 Protein KinaseCell Cycle ProteinsChromosomal Proteins, Non-HistoneDsn1 protein, S cerevisiaeProtein Tyrosine PhosphatasesSaccharomyces cerevisiae Proteins

Identifiers

PMID20923974
PMCPMC2998326

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.