SynthesisJournal of psychopharmacology (Oxford, England)2010
Suicide and schizophrenia: a systematic review of rates and risk factors.
Synthesis in Journal of psychopharmacology (Oxford, England), 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 317 papers, 14 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
317 citing papers in PubMed, 14 syntheses or guidelines pooled it, 831 citations in OpenAlex.
- The severity of dissociation and dissociative phenomena in non-affective psychosis: a systematic review and meta-analyses.BMC psychiatry · 2026Pooled it
- Polysomnographic Parameters in Schizoaffective Disorder: A Systematic Review and Meta-Analysis.Alpha psychiatry · 2026Pooled it
- Social connectedness and disconnectedness in individuals with recent onset psychosis and suicidal experiences: a systematic review of the evidence.BMC psychiatry · 2026Pooled it
- Effectiveness of Cognitive Behavioral Therapies Targeting Cognitive Biases and Beliefs in Schizophrenia-Spectrum Disorders: A Systematic Review and Meta-Analysis.Schizophrenia bulletin · 2026Pooled it
- MicroRNAs and suicidality: a systematic review and bioinformatic evaluation.Frontiers in psychiatry · 2026Pooled it
- Comparative efficacy of different types of exercise modalities on psychiatric symptomatology in patients with schizophrenia: a systematic review with network meta-analysis.Scientific reports · 2024Pooled it
- Suicidal Behaviors and Associated Factors Among Individuals with Gambling Disorders: A Meta-Analysis.Journal of gambling studies · 2023Pooled it
- Prevalence of suicide ideation, self-harm, and suicide among Chinese patients with schizophrenia: a systematic review and meta-analysis.Frontiers in public health · 2023Pooled it
- Worldwide prevalence of suicidal ideation and suicide plan among people with schizophrenia: a meta-analysis and systematic review of epidemiological surveys.Translational psychiatry · 2021Pooled it
- Prevalence of mental disorders among elderly men: a systematic review and meta-analysis.Sao Paulo medical journal = Revista paulista de medicina · 2020Pooled it
- Transition Experiences Following Psychiatric Hospitalization: A systematic Review of the Literature.Community mental health journal · 2019Pooled it
- Prevalence of suicide attempts in individuals with schizophrenia: a meta-analysis of observational studies.Epidemiology and psychiatric sciences · 2019Pooled it
- Suicide-related behaviours in schizophrenia in China: a comprehensive meta-analysis.Epidemiology and psychiatric sciences · 2019Pooled it
- The Role of Demoralization and Hopelessness in Suicide Risk in Schizophrenia: A Review of the Literature.Medicina (Kaunas, Lithuania) · 2019Pooled it
- Predictors of Mortality Following a Schizophrenia Spectrum Diagnosis: Evidence From the 20-Year Follow-up of the OPUS Randomized Controlled Trial.Schizophrenia bulletin · 2023Trial
- Pilot feasibility trial of a brief mobile-augmented suicide prevention intervention for serious mental illness.Psychiatric rehabilitation journal · 2023Trial
- Relating behaviours and therapeutic actions during AVATAR therapy dialogue: An observational study.The British journal of clinical psychology · 2021Trial
- Relationships between smartphone social behavior and relapse in schizophrenia: A preliminary report.Schizophrenia research · 2019Trial
- Socioeconomic Disparities in Post-Discharge Suicide Risk Among Individuals With Schizophrenia: A Population-Based Cohort Study in Korea.Journal of Korean medical science · 2026Article
- Differentiating indicators of vulnerability to deliberate self-harm in forensic and non-forensic patients with schizophrenia spectrum disorders: a multinational LASSO-based analysis.BMJ mental health · 2026Article
257 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Risk assessment is a core skill in psychiatry. Risk prediction for suicide in schizophrenia is known to be complex. We undertook a systematic review of all original studies concerning suicide in schizophrenia published since 2004. We found 51 data-containing studies (from 1281 studies screened) that met our inclusion criteria, and ranked these by standardized quality criteria. Estimates of rates of suicide and risk factors associated with later suicide were identified, and the risk factors were grouped according to type and strength of association with suicide. Consensus on the lifetime risk of suicide was a rate of approximately 5%. Risk factors with a strong association with later suicide included being young, male, and with a high level of education. Illness-related risk factors were important predictors, with number of prior suicide attempts, depressive symptoms, active hallucinations and delusions, and the presence of insight all having a strong evidential basis. A family history of suicide, and comorbid substance misuse were also positively associated with later suicide. The only consistent protective factor for suicide was delivery of and adherence to effective treatment. Prevention of suicide in schizophrenia will rely on identifying those individuals at risk, and treating comorbid depression and substance misuse, as well as providing best available treatment for psychotic symptoms.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.