ReviewJournal of psychopharmacology (Oxford, England)2010
Mortality trends in the general population: the importance of cardiorespiratory fitness.
Review in Journal of psychopharmacology (Oxford, England), 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03700671 (The Effects of Low-Volume High Intensity Interval Training and Circuit Training on Maximal Oxygen Uptake), which is not on this map. Cited by 244 papers, 20 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Effects of Low-Volume High Intensity Interval Training and Circuit Training on Maximal Oxygen Uptake
Who cites it
244 citing papers in PubMed, 20 syntheses or guidelines pooled it, 601 citations in OpenAlex.
- Response of VOPhysiological reports · 2025Pooled it
- Combined training in hypoxic environments improves cardiometabolic health in older adults: a systematic review and meta-analysis of randomized controlled trials.Frontiers in medicine · 2025Pooled it
- Impact of Secondary Amenorrhea on Cardiovascular Disease Risk in Physically Active Women: A Systematic Review and Meta-Analysis.Journal of the American Heart Association · 2024Pooled it
- Physical activity interventions for cardiopulmonary fitness in obese children and adolescents: a systematic review and meta-analysis.BMC pediatrics · 2023Pooled it
- Association of Preoperative High-Intensity Interval Training With Cardiorespiratory Fitness and Postoperative Outcomes Among Adults Undergoing Major Surgery: A Systematic Review and Meta-Analysis.JAMA network open · 2023Pooled it
- Association of physical activity and heart rate variability in people with overweight and obesity: A systematic review.F1000Research · 2023Pooled it
- The role of resistance exercise training for improving cardiorespiratory fitness in healthy older adults: a systematic review and meta-analysis.Age and ageing · 2022Pooled it
- Lifestyle changes in patients with non-alcoholic fatty liver disease: A systematic review and meta-analysis.PloS one · 2022Pooled it
- Effects of Short- and Long-Term Detraining on Maximal Oxygen Uptake in Athletes: A Systematic Review and Meta-Analysis.BioMed research international · 2022Pooled it
- Effects of high-intensity and moderate-intensity exercise training on cardiopulmonary function in patients with coronary artery disease: A meta-analysis.Frontiers in cardiovascular medicine · 2022Pooled it
- The Effect of Pre-operative Exercise Intervention on Patient Outcomes Following Bariatric Surgery: a Systematic Review and Meta-analysis.Obesity surgery · 2022Pooled it
- Effects of Exercise Training on Cardiopulmonary Function and Quality of Life in Elderly Patients with Pulmonary Fibrosis: A Meta-Analysis.International journal of environmental research and public health · 2021Pooled it
- Head-Out Water-Based Protocols to Assess Cardiorespiratory Fitness-Systematic Review.International journal of environmental research and public health · 2020Pooled it
- Sex Dimorphism of VOSports medicine (Auckland, N.Z.) · 2019Pooled it
- The association between cardiorespiratory fitness and the incidence of common mental health disorders: A systematic review and meta-analysis.Journal of affective disorders · 2019Pooled it
- Effects of Workplace-Based Physical Activity Interventions on Cardiorespiratory Fitness: A Systematic Review and Meta-Analysis of Controlled Trials.Sports medicine (Auckland, N.Z.) · 2019Pooled it
- Broad-spectrum physical fitness benefits of recreational football: a systematic review and meta-analysis.British journal of sports medicine · 2019Pooled it
- The effect of exercise training on clinical outcomes in patients with the metabolic syndrome: a systematic review and meta-analysis.Cardiovascular diabetology · 2017Pooled it
- Cardiorespiratory Fitness in Severe Mental Illness: A Systematic Review and Meta-analysis.Sports medicine (Auckland, N.Z.) · 2017Pooled it
- Depression Symptom Severity and Cardiorespiratory Fitness in Healthy and Depressed Adults: A Systematic Review and Meta-Analysis.Sports medicine (Auckland, N.Z.) · 2016Pooled it
184 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cardiorespiratory fitness (CRF) is not only an objective measure of habitual physical activity, but also a useful diagnostic and prognostic health indicator for patients in clinical settings. Although compelling evidence has shown that CRF is a strong and independent predictor of all-cause and cardiovascular disease mortality, the importance of CRF is often overlooked from a clinical perspective compared with other risk factors such as hypertension, diabetes, smoking, or obesity. Several prospective studies indicate that CRF is at least as important as the traditional risk factors, and is often more strongly associated with mortality. In addition, previous studies report that CRF appears to attenuate the increased risk of death associated with obesity. Most individuals can improve their CRF through regular physical activity. Several biological mechanisms suggest that CRF improves insulin sensitivity, blood lipid profile, body composition, inflammation, and blood pressure. Based on the evidence, health professionals should encourage their patients to improve CRF through regular physical activity.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.