Evidence map›Paper›PMID 20923711›Full record

ArticleVaccine2010

Forecasting the economic value of an Enterovirus 71 (EV71) vaccine.

Bruce Y Lee, Angela R Wateska, Rachel R Bailey, Julie H Y Tai, Kristina M Bacon, Kenneth J Smith

Abstract read
In one paragraph

Article in Vaccine, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 47 citations in OpenAlex.

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  20. Is a multivalent hand, foot, and mouth disease vaccine feasible?Human vaccines & immunotherapeutics · 2015
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Bruce Y LeePublic Health Computational and Operations Research (PHICOR), School of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, United States. BYL1@pitt.edu
Angela R Wateska
Rachel R Bailey
Julie H Y Tai
Kristina M Bacon
Kenneth J Smith
University of Pittsburgh · US

Funding

Training, Outreach & Diversity ComponentU54GM088491 · NIGMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI LAKOSKI, JOAN M · 2009 to 2018
$16.7M
NIGMS NIH HHS 1U54GM088491-0109NIGMS NIH HHS U54 GM088491
6 · The paper itself

Abstract

Enterovirus 71 (EV71) is a growing public health concern, especially in Asia. A surge of EV71 cases in 2008 prompted authorities in China to go on national alert. While there is currently no treatment for EV71 infections, vaccines are under development. We developed a computer simulation model to determine the potential economic value of an EV71 vaccine for children (<5 years old) in China. Our results suggest that routine vaccination in China (EV71 infection incidence ≈0.04%) may be cost-effective when vaccine cost is $25 and efficacy ≥70% or cost is $10 and efficacy ≥50%. For populations with higher infection risk (≥0.4%), a $50 or $75 vaccine would be highly cost-effective even when vaccine efficacy is as low as 50%.

Indexed as

ForecastingModels, EconomicChildComputer SimulationCost-Benefit AnalysisEnterovirus A, HumanEnterovirus InfectionsHumansViral VaccinesViral Vaccines

Identifiers

PMID20923711
PMCPMC2989421
OpenAlexW2090380214

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.