ReviewHead & neck oncology2010
Raman spectroscopy in head and neck cancer.
Review in Head & neck oncology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Current concepts and future of noninvasive procedures for diagnosing oral squamous cell carcinoma--a systematic review.Head & face medicine · 2015Pooled it
- Assessing the performance of QLQ-C30 in predicting all-cause mortality in community cancer patients.BMC cancer · 2025Article
- Advances in Raman spectroscopy for characterising oral cancer and oral potentially malignant disorders.Expert reviews in molecular medicine · 2024Review
- Diagnostic Biomarkers for Gestational Diabetes Mellitus Using Spectroscopy Techniques: A Systematic Review.Diseases (Basel, Switzerland) · 2023Review
- The emerging applications and advancements of Raman spectroscopy in pediatric cancers.Frontiers in oncology · 2023Review
- Raman Spectroscopy: A Potential Diagnostic Tool for Oral Diseases.Frontiers in cellular and infection microbiology · 2022Review
- Optical diagnosis of oral cavity lesions by label-free Raman spectroscopy.Biomedical optics express · 2021Article
- Diagnosing Hirschsprung disease by detecting intestinal ganglion cells using label-free hyperspectral microscopy.Scientific reports · 2021Article
- Molecular margins in head and neck cancer: Current techniques and future directions.Oral oncology · 2020Review
- Human salivary Raman fingerprint as biomarker for the diagnosis of Amyotrophic Lateral Sclerosis.Scientific reports · 2020Article
- The use of optical coherence tomography and convolutional neural networks to distinguish normal and abnormal oral mucosa.Journal of biophotonics · 2020Article
- Hyperspectral Raman microscopy can accurately differentiate single cells of different human thyroid nodules.Biomedical optics express · 2019Article
- In vivo Raman spectroscopic characteristics of different sites of the oral mucosa in healthy volunteers.Clinical oral investigations · 2019Article
- In-vivo optical imaging in head and neck oncology: basic principles, clinical applications and future directions.International journal of oral science · 2018Review
- Proof-of-concept Raman spectroscopy study aimed to differentiate thyroid follicular patterned lesions.Scientific reports · 2017Article
- Raman Spectroscopy of Head and Neck Cancer: Separation of Malignant and Healthy Tissue Using Signatures Outside the "Fingerprint" Region.Biosensors · 2017Article
- Article
- Investigation of the potential of Raman spectroscopy for oral cancer detection in surgical margins.Laboratory investigation; a journal of technical methods and pathology · 2015Article
- Amide proton transfer-weighted imaging of the head and neck at 3 T: a feasibility study on healthy human subjects and patients with head and neck cancer.NMR in biomedicine · 2014Article
- Raman difference spectroscopy: a non-invasive method for identification of oral squamous cell carcinoma.Biomedical optics express · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
Abstract
In recent years there has been much interest in the use of optical diagnostics in cancer detection. Early diagnosis of cancer affords early intervention and greatest chance of cure. Raman spectroscopy is based on the interaction of photons with the target material producing a highly detailed biochemical 'fingerprint' of the sample. It can be appreciated that such a sensitive biochemical detection system could confer diagnostic benefit in a clinical setting. Raman has been used successfully in key health areas such as cardiovascular diseases, and dental care but there is a paucity of literature on Raman spectroscopy in Head and Neck cancer. Following the introduction of health care targets for cancer, and with an ever-aging population the need for rapid cancer detection has never been greater. Raman spectroscopy could confer great patient benefit with early, rapid and accurate diagnosis. This technique is almost labour free without the need for sample preparation. It could reduce the need for whole pathological specimen examination, in theatre it could help to determine margin status, and finally peripheral blood diagnosis may be an achievable target.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.