Evidence map›Paper›PMID 20922424›Full record

ArticleParasitology research2011

prag01, a novel deltamethrin-resistance-associated gene from Culex pipiens pallens.

Jin Zhang, Mifang Yang, Weijie Wang, Haibo Sun, Yang Xu, Lei Ma, Yan Sun, Changliang Zhu

Abstract read
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In one paragraph

Article in Parasitology research, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. The Genome ofGenes · 2022
    Article
  4. Article
  5. Article
  6. Article
  7. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jin ZhangDepartment of Pathogen Biology, Nanjing Medical University, Nanjing, Jiangsu, 210029, People's Republic of China.
Mifang Yang
Weijie Wang
Haibo Sun
Yang Xu
Lei Ma
Yan Sun
Changliang Zhu

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The prag01 gene (GenBank accession no. EU073017) was cloned from Culex pipiens pallens. An open reading frame of 270 bp was found to encode a putative 89-amino-acid protein which has the highest homology with Culex quinquefasciatus and Anopheles funestus. Real-time quantitative PCR analysis demonstrated that the transcription level of prag01 gene in deltamethrin-resistant strain was 1.65-fold higher than in deltamethrin-susceptible strain of C. pipiens pallens. Overexpression of prag01 gene in the mosquito C6/36 cells showed better prolification than the cells with empty vector when treated by deltamethrin. Our data for the first time approved that prag01 gene might play some role in the development of deltamethrin resistance in C. pipiens pallens.

Indexed as

Gene ExpressionGenes, InsectAmino Acid SequenceAnimalsBase SequenceBlotting, WesternCells, CulturedCell SurvivalCloning, MolecularCulexDrug ResistanceGene Expression ProfilingInsecticidesInsect ProteinsMolecular Sequence DataNitrilesdecamethrinInsecticidesInsect ProteinsNitrilesPyrethrins

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.