ArticleParasitology research2011
Larvicidal activity of metabolites from the endophytic Podospora sp. against the malaria vector Anopheles gambiae.
Article in Parasitology research, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
19 citing papers in PubMed.
- What are the 100 most cited fungal genera?Studies in mycology · 2024Article
- High-Quality Genome Assemblies of 4 Members of the Podospora anserina Species Complex.Genome biology and evolution · 2024Article
- Article
- Fungal Microbiome of Alive and Dead Korean Fir in its Native Habitats.Mycobiology · 2024Article
- Biotechnological Potential of Microorganisms for Mosquito Population Control and Reduction in Vector Competence.Insects · 2023Review
- Complementary Strategies to Unlock Biosynthesis Gene Clusters Encoding Secondary Metabolites in the Filamentous FungusJournal of fungi (Basel, Switzerland) · 2022Article
- Functional Characterization of the GATA-Type Transcription Factor PaNsdD in the Filamentous Fungus Podospora anserina and Its Interplay with the Sterigmatocystin Pathway.Applied and environmental microbiology · 2022Article
- Biosynthetic gene clusters and the evolution of fungal chemodiversity.Natural product reports · 2020Article
- A Small Horizontally Transferred Gene Cluster Contributes to the Sporulation of Alternaria alternata.Genome biology and evolution · 2019Article
- Genomic features and evolution of the conditionally dispensable chromosome in the tangerine pathotype of Alternaria alternata.Molecular plant pathology · 2019Article
- Chromosome rearrangements shape the diversification of secondary metabolism in the cyclosporin producing fungus Tolypocladium inflatum.BMC genomics · 2019Article
- Larvicidal, Histopathological, Antibacterial Activity of Indigenous FungusFrontiers in microbiology · 2019Article
- The birth, evolution and death of metabolic gene clusters in fungi.Nature reviews. Microbiology · 2018Review
- Mosquito larvicidal activity of silver nanoparticles synthesised using actinobacterium, Streptomyces sp. M25 against Anopheles subpictus, Culex quinquefasciatus and Aedes aegypti.Journal of parasitic diseases : official organ of the Indian Society for Parasitology · 2015Article
- Fungal metabolic gene clusters-caravans traveling across genomes and environments.Frontiers in microbiology · 2015Review
- The major bioactive components of seaweeds and their mosquitocidal potential.Parasitology research · 2014Review
- The transcriptional response to nonself in the fungus Podospora anserina.G3 (Bethesda, Md.) · 2013Article
- bZIP transcription factors affecting secondary metabolism, sexual development and stress responses in Aspergillus nidulans.Microbiology (Reading, England) · 2013Article
- An Aspergillus nidulans bZIP response pathway hardwired for defensive secondary metabolism operates through aflR.Molecular microbiology · 2012Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In a screening for natural products with mosquito larvicidal activities, the endophytic fungus Podospora sp. isolated from the plant Laggera alata (Asteraceae) was conspicuous. Two xanthones, sterigmatocystin (1) and secosterigmatocystin (2), and an anthraquinone derivative (3) 13-hydroxyversicolorin B were isolated after fermentation on M(2) medium. These compounds were characterised using spectroscopic and X-ray analysis and examined against third instar larvae of Anopheles gambiae. The results demonstrated that compound 1 was the most potent one with LC(50) and LC(90) values of 13.3 and 73.5 ppm, respectively. Over 95% mortality was observed at a concentration 100 ppm after 24 h. These results compared farvorably with the commercial larvicide pylarvex® that showed 100% mortality at the same concentration. Compound 3 was less potent and had an LC(50) of 294.5 ppm and over 95% mortality was achieved at a concentration of 1,000 ppm. Secosterigmatocystin (2) revealed relatively weak activity and therefore LC values were not determined.
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