Evidence map›Paper›PMID 20922391›Full record

ArticleEuropean radiology2011

MR enterography versus capsule endoscopy in paediatric patients with suspected Crohn's disease.

Emanuele Casciani, Gabriele Masselli, Giovanni Di Nardo, Elisabetta Polettini, Luca Bertini, Salvatore Oliva, Irene Floriani, Salvatore Cucchiara, Gianfranco Gualdi

Registry-linked trialAbstract read
PubMed Publisher
In one paragraph

Article in European radiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02182947 (Comparison of the Use of Wireless Capsule Endoscopy With Magnetic Resonance Enterography in Children With Inflammatory Bowel Disease), which is not on this map. Cited by 28 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 4 pooled it
5.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02182947 nacompletednot on this mapstarted 2012, after this paper: background citation

Comparison of the Use of Wireless Capsule Endoscopy With Magnetic Resonance Enterography in Children With Inflammatory Bowel Disease

TypeinterventionalSponsorChildren's Mercy Hospital Kansas CityRan2012 to 2018Enrolled45ConditionsIBDArmsCapsule endoscopy
3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 4 syntheses or guidelines pooled it, 70 citations in OpenAlex.

  1. Saudi consensus guidance for the diagnosis and management of inflammatory bowel disease in children and adolescents.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association · 2025
    Guideline
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Capsule endoscopy: Current status and role in Crohn's disease.World journal of gastrointestinal endoscopy · 2018
    Review
  14. Review
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Capsule endoscopy in pediatrics: a 10-years journey.World journal of gastroenterology · 2014
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Emanuele CascianiRadiology DEA, Azienda Policlinico Umberto I, La Sapienza University, Via del Policlinico, 155, 00166 Rome, Italy. emanuelecasciani@gmail.com
Gabriele Masselli
Giovanni Di Nardo
Elisabetta Polettini
Luca Bertini
Salvatore Oliva
Irene Floriani
Salvatore Cucchiara
Gianfranco Gualdi
Policlinico Umberto I · ITSapienza University of Rome · ITMario Negri Institute for Pharmacological Research · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe aim of this prospective study was to compare the diagnostic yield of MR enterography (MRE) with small-bowel capsule endoscopy (SBCE) in paediatric patients with suspected Crohn's disease (CD).

methodsPaediatric patients with suspected CD were considered eligible to be enrolled in the study. All patients underwent diagnostic work-up including 1.5-T MRE, ileo-colonoscopy and oesophagogastroduodenoscopy. SBCE was not performed if MRE showed SB stricture or extra-intestinal findings consistent with symptoms.

resultsSixty consecutive paediatric patients (36 male; average age 14) were enrolled into the study. A positive diagnosis for CD was made in 19 patients, 29 had a negative result and 12 were affected by other gastro-intestinal conditions. SBCE was performed in 37 patients (61.7%); 23 patients were excluded (strictures in five, extra-intestinal findings in 11 and parents' refusal in seven cases). The accuracy, sensitivity, and specificity of MRE and SBCE were 98.3%, 100%, 97.6%, and 91.9%, 90.9%, 92.3%, respectively.

conclusionBoth MRE and SBCE are accurate methods for patients with suspected CD. MRE can be used as a primary imaging technique in suspected CD, in that it allows access to the ileal stricture, which forms a contra-indication for SBCE and provides extra-intestinal information.

Indexed as

AdolescentChildColitis, UlcerativeColonoscopyCrohn DiseaseEndoscopyFemaleHumansIntestine, SmallMagnetic Resonance ImagingMalePediatricsProspective StudiesReproducibility of ResultsSensitivity and Specificity

Identifiers

PMID20922391
OpenAlexW2060061705

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.