Trial reportCritical care (London, England)2010
Refeeding syndrome influences outcome of anorexia nervosa patients in intensive care unit: an observational study.
Trial report in Critical care (London, England), 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03055104 (Management and Treatment of Patients With Severe Malnutrition in Intensive Care Unit), which is not on this map. Cited by 33 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Management and Treatment of Patients With Severe Malnutrition in Intensive Care Unit: a Registry
Who cites it
33 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Incidence and mortality of refeeding syndrome in critically ill patients: a systematic review and meta-analysis.Scientific reports · 2026Pooled it
- Autonomic Nervous System Function in Anorexia Nervosa: A Systematic Review.Frontiers in neuroscience · 2021Pooled it
- The use of enteral nutrition in the treatment of eating disorders: a systematic review.Eating and weight disorders : EWD · 2019Pooled it
- All-cause and cause-specific mortality risk in individuals with eating disorders: systematic review and meta-analysis of relative risk and aggravating or attenuating factors.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2026Article
- Development and validation of a prediction model for refeeding syndrome in ICU patients receiving mechanical ventilation and enteral nutrition support: a single-center retrospective study from China.Frontiers in medicine · 2026Article
- Risk Factors and Prognostic Effects of Refeeding Syndrome in Malnourished Elderly Patients During Nutritional Support.Journal of nutrition and metabolism · 2026Article
- "I could be living a totally different life right now": lived experience and caregiver perspectives on the prevention of eating disorders.Journal of eating disorders · 2025Article
- Medical management and differential diagnosis of restrictive eating disorders in men: a case study report with co-produced recommendations.Journal of eating disorders · 2025Article
- The Hungry Heart: Managing Cardiogenic Shock in Patients with Severe Anorexia Nervosa-A Case Report Series.Journal of clinical medicine · 2025Article
- Review
- Dual Hepatic Injury from Refeeding Syndrome and Starvation in a Malnourished Woman After Bariatric Surgery: A Case Report.The American journal of case reports · 2024Article
- Predicting extremely low body weight from 12-lead electrocardiograms using a deep neural network.Scientific reports · 2024Article
- Refeeding Syndrome.Deutsches Arzteblatt international · 2023Review
- Anorexia nervosa: practical implications for the anaesthetist.BJA education · 2023Review
- Article
- Psychiatric and medical comorbidities of eating disorders: findings from a rapid review of the literature.Journal of eating disorders · 2022Review
- Autonomic nervous system function in women with anorexia nervosa.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2022Article
- The Refeeding Syndrome: a neglected but potentially serious condition for inpatients. A narrative review.Internal and emergency medicine · 2021Review
- Management of Refeeding Syndrome in Medical Inpatients.Journal of clinical medicine · 2019Review
- Nutritional Management and Outcomes in Malnourished Medical Inpatients: Anorexia Nervosa.Journal of clinical medicine · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionData on the epidemiology and management of anorexia nervosa (AN) in the intensive care unit (ICU) are scarce. The aim of this study was to evaluate the prevalence and associated morbidity and mortality of AN in French ICUs.
methodsWe randomly selected 30 ICUs throughout France. Thereafter, we retrospectively analyzed all patients with AN admitted to any of these 30 ICUs between May 2006 and May 2008. We considered demographic data, diagnosis at admission and complications occurring during the stay, focusing on refeeding syndrome and management of refeeding.
resultsEleven of the 30 ICUs participated in the retrospective study, featuring 68 patients, including 62 women. Average body mass index at the admission was 12 ± 3 kg/m2. Twenty one were mechanically ventilated, mainly for neurological reasons. The reported average calorie intake was 22.3 ± 13 kcal/kg/24 h. Major diagnoses at admission were metabolic problems, refeeding survey and voluntary drug intoxication and infection. The most common complications were metabolic, hematological, hepatic, and infectious events, of which 10% occurred during refeeding. Seven patients developed refeeding syndrome. At day one, the average calorie intake was higher for patients who developed refeeding syndrome (23.2 ± 5 Kcal/kg/j; n = 7) versus patients without refeeding syndrome (14.1 ± 3 Kcal/kg/j; n = 61) P = 0.02. Seven patients died, two from acute respiratory distress syndrome and five from multiorgan-failure associated with major hydroelectrolytic problems.
conclusionsThe frequency of AN in ICU patients is very low and the crude mortality in this group is about 10%. Prevention and early-detection of refeeding syndrome is the key point.
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