Evidence map›Paper›PMID 20919699›Full record

ArticleBiomacromolecules2010

Adhesive performance of biomimetic adhesive-coated biologic scaffolds.

John L Murphy, Laura Vollenweider, Fangmin Xu, Bruce P Lee

Abstract read
In one paragraph

Article in Biomacromolecules, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
6.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 125 citations in OpenAlex.

  1. Article
  2. Comparison of the Impact of NaIOACS applied materials & interfaces · 2024
    Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Review
  10. Article
  11. Review
  12. Article
  13. Adhesive Cements That Bond Soft Tissue Ex Vivo.Materials (Basel, Switzerland) · 2019
    Article
  14. Marine-Inspired Polymers in Medical Adhesion.European polymer journal · 2019
    Article
  15. Multifunctional Biomedical Adhesives.Advanced healthcare materials · 2019
    Review
  16. Article
  17. Review
  18. Article
  19. Review
  20. Recent approaches in designing bioadhesive materials inspired by mussel adhesive protein.Journal of polymer science. Part A, Polymer chemistry · 2017
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

John L MurphyNerites Corporation, Madison, Wisconsin 53719, United States.
Laura Vollenweider
Fangmin Xu
Bruce P Lee

Funding

WATER DISTRIB:PHYSICAL PROPERT:PIZZA &LMPS MOZZARELLA CHEESES:EARLY STAGE MATURP41RR002301 · NCRR · UNIVERSITY OF WISCONSIN-MADISON · PI KEUTSCH, FRANK · 1985 to 2011
$13.0M
900 MHz NMR Spectrometer Biomolecular InvestigationsP41GM066326 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI MARKLEY, JOHN L · 2002 to 2006
$5.0M
Bioadhesive Membrane Construct for Hernia RepairR43DK083199 · NIDDK · NERITES CORPORATION · PI LEE, BRUCE P · 2008 to 2008
$116k
WIDE-BORE 9.4 TESLA NMR SPECTROMETER FOR UW-MADISONS10RR002781 · NCRR · UNIVERSITY OF WISCONSIN MADISON · PI MARKLEY, JOHN L · 1986 to 1986
–
CONSOLE UPGRADES FOR NMR FACILITYS10RR008438 · NCRR · UNIVERSITY OF WISCONSIN MADISON · PI MARKLEY, JOHN L · 1993 to 1993
–
NCRR NIH HHS P41 RR002301NCRR NIH HHS P41RR02301NCRR NIH HHS S10 RR002781NCRR NIH HHS S10 RR008438NIDDK NIH HHS 1R43DK083199-01NIDDK NIH HHS R43 DK083199NIGMS NIH HHS P41 GM066326NIGMS NIH HHS P41GM66326
6 · The paper itself

Abstract

Surgical repair of a discontinuity in traumatized or degenerated soft tissues is traditionally accomplished using sutures. A current trend is to reinforce this primary repair with surgical grafts, meshes, or patches secured with perforating mechanical devices (i.e., sutures, staples, or tacks). These fixation methods frequently lead to chronic pain and mesh detachment. We developed a series of biodegradable adhesive polymers that are synthetic mimics of mussel adhesive proteins (MAPs), composed of 3,4-dihydroxyphenylalanine (DOPA)-derivatives, polyethylene glycol (PEG), and polycaprolactone (PCL). These polymers can be cast into films, and their mechanical properties, extent of swelling, and degradation rate can be tailored through the composition of the polymers as well as blending with additives. When coated onto a biologic mesh used for hernia repair, these adhesive constructs demonstrated adhesive strengths significantly higher than fibrin glue. With further development, a precoated bioadhesive mesh may represent a new surgical option for soft tissue repair.

Indexed as

Biocompatible MaterialsDihydroxyphenylalanineMolecular StructurePolymersProteinsadhesive protein, musselBiocompatible MaterialsDihydroxyphenylalaninePolymersProteins

Identifiers

PMID20919699
PMCPMC3027843
OpenAlexW2087570215

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.