Evidence map›Paper›PMID 20890654›Full record

ArticleAIDS and behavior2011

Concurrent sexual partnerships and primary HIV infection: a critical interaction.

Jeffrey W Eaton, Timothy B Hallett, Geoffrey P Garnett

Abstract read
In one paragraph

Article in AIDS and behavior, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 81 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
81citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

81 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. A Review of Network Models for HIV Spread.Journal of acquired immune deficiency syndromes (1999) · 2025
    Pooled it
  2. Concurrent partnerships and HIV: an inconvenient truth.Journal of the International AIDS Society · 2011
    Pooled it
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21 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jeffrey W EatonDepartment of Infectious Disease Epidemiology, Imperial College London, St. Mary's Campus, Norfolk Place, London, W2 1PG, UK. jeffrey.eaton08@imperial.ac.uk
Timothy B Hallett
Geoffrey P Garnett

Funding

Wellcome Trust 084401
6 · The paper itself

Abstract

The combination of long-term concurrent sexual partnerships and high infectiousness early in HIV infection has been suggested as a key driver of the extensive spread of HIV in general populations in sub-Saharan Africa, but this has never been scientifically investigated. We use a mathematical model to simulate HIV spreading on sexual networks with different amounts of concurrency. The models show that if HIV infectiousness is constant over the duration of infection, the amount of concurrency has much less influence on HIV spread compared to when infectiousness varies over three stages of infection with high infectiousness in the first months. The proportion of transmissions during primary infection is sensitive to the amount of concurrency and, in this model, is estimated to be between 16 and 28% in spreading epidemics with increasing concurrency. The sensitivity of epidemic spread to the amount of concurrency is greater than predicted by models that do not include primary HIV infection.

Indexed as

Sexual BehaviorSexual PartnersAfrica South of the SaharaDisease OutbreaksFemaleHIV InfectionsHumansMaleModels, TheoreticalRisk Factors

Identifiers

PMID20890654
PMCPMC3520057

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.