Evidence map›Paper›PMID 20889894›Full record

ArticleThe American journal of tropical medicine and hygiene2010

Immunoblot diagnostic test for neurognathostomiasis.

Pewpan M Intapan, Piyarat Khotsri, Jaturat Kanpittaya, Verajit Chotmongkol, Kittisak Sawanyawisuth, Wanchai Maleewong

Abstract read
In one paragraph

Article in The American journal of tropical medicine and hygiene, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Spinal epidural hematoma and gnathostomiasis.The American journal of tropical medicine and hygiene · 2015
    Article
  10. Article
  11. Article
  12. Article
  13. Differential diagnosis of CNS angiostrongyliasis: a short review.Hawai'i journal of medicine & public health : a journal of Asia Pacific Medicine & Public Health · 2013
    Review
  14. Autochthonous gnathostomiasis, Brazil.Emerging infectious diseases · 2012
    Article
  15. Identification of immunodominant peptides from Gnathostoma binucleatum.The American journal of tropical medicine and hygiene · 2012
    Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Pewpan M IntapanDepartment of Parasitology, Radiology, and Medicine, Faculty of Medicine, and Research and Diagnosis Center for Emerging Infectious Disease, Khon Kaen University, Khon Kaen, Thailand. pewpan@kku.ac.th
Piyarat Khotsri
Jaturat Kanpittaya
Verajit Chotmongkol
Kittisak Sawanyawisuth
Wanchai Maleewong

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neurognathostomiasis is a rare but severe form of human gnathostomiasis. Diagnosis of neurognathostomiasis is made presumably by using clinical manifestations. Serologic tests for neurognathostomiasis are not widely available and limited. We studied 12 patients with diagnoses of neurognathostomiasis at Srinagarind Hospital, Khon Kaen University, Thailand. There were three types of neurognathostomiasis (five patients with intracerebral hemorrhage, one patient with subarachnoid hemorrhage, and six patients with myelitis). All patients were tested for antibodies against Gnathostoma spinigerum by an immunoblotting technique. The sensitivity and specificity of the 21-kD and 24-kD diagnostic bands were 83.3% and 100%, and 91.7% and 100%, respectively. The sensitivity, specificity, positive predictive value, and negative predictive value for the 21-kD and 24-kD diagnostic bands were all 100%. Both diagnostic bands are a helpful diagnostic tool for neuro gnathostomiasis and show good diagnostic properties.

Indexed as

AdultAnimalsAntibodies, HelminthAntigens, HelminthCentral Nervous System HelminthiasisCerebral HemorrhageFemaleGnathostomaHumansImmunoblottingImmunoglobulin GLarvaMaleMiddle AgedMyelitisPredictive Value of TestsAntibodies, HelminthAntigens, HelminthImmunoglobulin G

Identifiers

PMID20889894
PMCPMC2946771

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.