ArticleApplied and environmental microbiology2010
Exploring the low-pressure growth limit: evolution of Bacillus subtilis in the laboratory to enhanced growth at 5 kilopascals.
Article in Applied and environmental microbiology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
17 citing papers in PubMed.
- Air pressure as a driver of plant-specific microbial responses in the rhizosphere.Environmental microbiome · 2025Article
- Biocomposite thermoplastic polyurethanes containing evolved bacterial spores as living fillers to facilitate polymer disintegration.Nature communications · 2024Article
- Polyextremophile engineering: a review of organisms that push the limits of life.Frontiers in microbiology · 2024Review
- Bridging the gap between microbial limits and extremes in space: space microbial biotechnology in the next 15 years.Microbial biotechnology · 2022Article
- The Hypopiezotolerant Bacterium,Life (Basel, Switzerland) · 2020Article
- Microbiome and ecology of a hot spring-microbialite system on the Trans-Himalayan Plateau.Scientific reports · 2020Article
- What do we know about the influence of vacuum on bacterial biocenosis used in environmental biotechnologies?Applied microbiology and biotechnology · 2020Review
- Experimental Design, Population Dynamics, and Diversity in Microbial Experimental Evolution.Microbiology and molecular biology reviews : MMBR · 2018Review
- Twenty-Three Species of Hypobarophilic Bacteria Recovered from Diverse Ecosystems Exhibit Growth under Simulated Martian Conditions at 0.7 kPa.Astrobiology · 2016Article
- Experimental evolution of enhanced growth by Bacillus subtilis at low atmospheric pressure: genomic changes revealed by whole-genome sequencing.Applied and environmental microbiology · 2015Article
- Carbon monoxide as a metabolic energy source for extremely halophilic microbes: implications for microbial activity in Mars regolith.Proceedings of the National Academy of Sciences of the United States of America · 2015Article
- Exposure of Bacillus subtilis to low pressure (5 kilopascals) induces several global regulons, including those involved in the SigB-mediated general stress response.Applied and environmental microbiology · 2014Article
- Growth of Serratia liquefaciens under 7 mbar, 0°C, and CO2-enriched anoxic atmospheres.Astrobiology · 2013Article
- Growth of Carnobacterium spp. from permafrost under low pressure, temperature, and anoxic atmosphere has implications for Earth microbes on Mars.Proceedings of the National Academy of Sciences of the United States of America · 2013Article
- Effect of the Bacillus atrophaeus subsp. globigii Spo0F H101R mutation on strain fitness.Applied and environmental microbiology · 2012Article
- Increased competitive fitness of Bacillus subtilis under nonsporulating conditions via inactivation of pleiotropic regulators AlsR, SigD, and SigW.Applied and environmental microbiology · 2012Article
- Increased fitness and alteration of metabolic pathways during Bacillus subtilis evolution in the laboratory.Applied and environmental microbiology · 2011Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Growth of Bacillus subtilis cells, normally adapted at Earth-normal atmospheric pressure (∼101.3 kPa), was progressively inhibited by lowering of pressure in liquid LB medium until growth essentially ceased at 2.5 kPa. Growth inhibition was immediately reversible upon return to 101.3 kPa, albeit at a slower rate. A population of B. subtilis cells was cultivated at the near-inhibitory pressure of 5 kPa for 1,000 generations, where a stepwise increase in growth was observed, as measured by the turbidity of 24-h cultures. An isolate from the 1,000-generation population was obtained that showed an increase in fitness at 5 kPa when compared to the ancestral strain or a strain obtained from a parallel population that evolved for 1,000 generations at 101.3 kPa. The results from this preliminary study have implications for understanding the ability of terrestrial microbes to grow in low-pressure environments such as Mars.
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