ArticleLearning & memory (Cold Spring Harbor, N.Y.)2010
The central amygdala projection to the substantia nigra reflects prediction error information in appetitive conditioning.
Article in Learning & memory (Cold Spring Harbor, N.Y.), 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
36 citing papers in PubMed.
- Reduction in Reward-Driven Behavior Depends on the Basolateral But Not Central Nucleus of the Amygdala in Female Rats.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Unravelling the nexus of stroke and dementia: Deciphering the role of secondary neurodegeneration in orchestrating cognitive decline.Neuroprotection (Chichester, England) · 2025Review
- A dual-pathway architecture enables chronic stress to disrupt agency and promote habit formation.bioRxiv : the preprint server for biology · 2024Article
- A Computational Model for the Simulation of Prepulse Inhibition and Its Modulation by Cortical and Subcortical Units.Brain sciences · 2024Article
- The role of genetically distinct central amygdala neurons in appetitive and aversive responding assayed with a novel dual valence operant conditioning paradigm.bioRxiv : the preprint server for biology · 2023Article
- Cerebellar control of fear learning via the cerebellar nuclei-Multiple pathways, multiple mechanisms?Frontiers in systems neuroscience · 2023Review
- Temporal prediction error triggers amygdala-dependent memory updating in appetitive operant conditioning in rats.Frontiers in behavioral neuroscience · 2022Article
- Cell-type-specific disruption of PERK-eIF2α signaling in dopaminergic neurons alters motor and cognitive function.Molecular psychiatry · 2021Article
- The transition to compulsion in addiction.Nature reviews. Neuroscience · 2020Review
- Ventral Tegmental Dopamine Neurons Participate in Reward Identity Predictions.Current biology : CB · 2019Article
- Predicting extinction phenotype to optimize fear reduction.Psychopharmacology · 2019Article
- Reinforcement omission effects in rats with bilateral lesions in the substantia nigra pars compacta and ventral tegmental area.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2019Article
- Loss of One Engrailed1 Allele Enhances Induced α-Synucleinopathy.Journal of Parkinson's disease · 2019Article
- Abundant collateralization of temporal lobe projections to the accumbens, bed nucleus of stria terminalis, central amygdala and lateral septum.Brain structure & function · 2017Article
- Article
- The Effects of Age, from Young to Middle Adulthood, and Gender on Resting State Functional Connectivity of the Dopaminergic Midbrain.Frontiers in human neuroscience · 2017Article
- A GABAergic Projection from the Centromedial Nuclei of the Amygdala to Ventromedial Prefrontal Cortex Modulates Reward Behavior.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2016Article
- Consolidation of altered associability information by amygdala central nucleus.Neurobiology of learning and memory · 2016Article
- Neural correlates of two different types of extinction learning in the amygdala central nucleus.Nature communications · 2016Article
- Mini-review: Prediction errors, attention and associative learning.Neurobiology of learning and memory · 2016Review
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3 authors.
Funding
Abstract
The central amygdala nucleus (CeA) plays a critical role in cognitive processes beyond fear conditioning. For example, intact CeA function is essential for enhancing attention to conditioned stimuli (CSs). Furthermore, this enhanced attention depends on the CeA's connections to the nigrostriatal system. In the current study, we examined the role of the CeA's connections to two midbrain dopamine regions, the substantia nigra pars compacta (SNc) and the ventral tegmental area (VTA), in processing CS information when predictions of reward or nonreward were confirmed or disconfirmed. Initially, two different retrograde tracers were injected into the SNc and the VTA of rats, to label CeA cells. Different groups of rats then received a visual CS either paired or unpaired with food. Finally, Fos induction was assessed after a test session in which rats were exposed to the visual CS alone or paired with food. Colabeling of Fos and the retrograde tracer(s) showed that CeA neurons projecting to the SNc, but not to the VTA, were engaged in processing CS information when the training and testing conditions differed. These results suggest that the CeA-nigral pathway represents prediction error information during appetitive conditioning.
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