Evidence map›Paper›PMID 20889712›Full record

ReviewGenes & development2010

Current views on the function of the lymphatic vasculature in health and disease.

Yingdi Wang, Guillermo Oliver

Open access · diamondAbstract readReview
In one paragraph

Review in Genes & development, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 97 papers.

0numbers the graph read from it
0cells of the map it votes in
97citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

97 citing papers in PubMed, 187 citations in OpenAlex.

  1. Article
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  13. Review
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  15. Role of the Renal Lymphatic System in Heart Failure.Current heart failure reports · 2023
    Review
  16. Article
  17. Article
  18. Review
  19. Review
  20. Article

37 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Yingdi WangDepartment of Genetics and Tumor Cell Biology, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, USA.
Guillermo Oliver
St. Jude Children's Research Hospital · US

Funding

Prox1 in Mammalian LymphangiogenesisR01HL073402 · NHLBI · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI OLIVER, GUILLERMO C · 2003 to 2020
$7.3M
NHLBI NIH HHS R01 HL073402
6 · The paper itself

Abstract

The lymphatic vascular system is essential for lipid absorption, fluid homeostasis, and immune surveillance. Until recently, lymphatic vessel dysfunction had been associated with symptomatic pathologic conditions such as lymphedema. Work in the last few years had led to a better understanding of the functional roles of this vascular system in health and disease. Furthermore, recent work has also unraveled additional functional roles of the lymphatic vasculature in fat metabolism, obesity, inflammation, and the regulation of salt storage in hypertension. In this review, we summarize the functional roles of the lymphatic vasculature in health and disease.

Indexed as

AnimalsHumansLymphatic DiseasesLymphatic Vessels

Identifiers

PMID20889712
PMCPMC2947764
OpenAlexW2013355011

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.