ArticleHearing research2010
Neuroimaging with near-infrared spectroscopy demonstrates speech-evoked activity in the auditory cortex of deaf children following cochlear implantation.
Article in Hearing research, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01256229 (OUTCOMES IN CHILDREN WITH DEVELOPMENTAL DELAY AND DEAFNESS), which is not on this map. Cited by 57 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Outcomes in children with developmental delay and deafness: a prospective, randomized trial
Who cites it
57 citing papers in PubMed, 1 synthesis or guideline pooled it, 121 citations in OpenAlex.
- Functional Near-Infrared Spectroscopy in the Study of Speech and Language Impairment Across the Life Span: A Systematic Review.American journal of speech-language pathology · 2020Pooled it
- Executive function and language: a behavioural and functional near-infrared spectroscopy study in 23 normally hearing children and one deaf child with cochlear implants.Frontiers in human neuroscience · 2026Review
- Vibrotactile speech cues are associated with enhanced auditory processing in middle and superior temporal gyri.Scientific reports · 2025Article
- Preliminary evidence for enhanced auditory cortex activation and mental development after gene therapy in children with autosomal recessive deafness 9.Nature human behaviour · 2025Article
- Article
- Imaging the developing brain with near-infrared spectroscopy in cochlear implanted children.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- A narrative review of functional near-infrared spectroscopy (fNIRS) applications in hearing loss, tinnitus and vestibular disorders.Frontiers in neuroscience · 2025Review
- Investigating Hemodynamic Patterns During Beat Processing in Cochlear Implant Users: Insights from a Finger Tapping Study.Auditory perception & cognition · 2025Article
- Intra-subject test-retest reliability for auditory-evoked functional near-infrared spectroscopy responses: effects of systemic physiology correction.Neurophotonics · 2025Article
- Early-stage use of hearing aids preserves auditory cortical structure in children with sensorineural hearing loss.Cerebral cortex (New York, N.Y. : 1991) · 2024Article
- Sound Level Changes the Auditory Cortical Activation Detected with Functional Near-Infrared Spectroscopy.Brain topography · 2023Article
- Brightening the Study of Listening Effort with Functional Near-Infrared Spectroscopy: A Scoping Review.Seminars in hearing · 2023Article
- Functional near-infrared spectroscopy in pediatric clinical research: Different pathophysiologies and promising clinical applications.Neurophotonics · 2023Article
- Controlling jaw-related motion artifacts in functional near-infrared spectroscopy.Journal of neuroscience methods · 2023Article
- Dynamic networks differentiate the language ability of children with cochlear implants.Frontiers in neuroscience · 2023Article
- The Effects of Cortical Reorganization and Applications of Functional Near-Infrared Spectroscopy in Deaf People and Cochlear Implant Users.Brain sciences · 2022Review
- Functional localization of audiovisual speech using near infrared spectroscopy.Brain topography · 2022Article
- Article
- Functional Reorganization of the Central Auditory System in Children with Single-Sided Deafness: A Protocol Using fNIRS.Brain sciences · 2022Article
- Consistency of children's hemodynamic responses during spontaneous speech.Neurophotonics · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 6 institutions in 1 country.
Funding
Abstract
Cochlear implants (CI) are commonly used to treat deafness in young children. While many factors influence the ability of a deaf child who is hearing through a CI to develop speech and language skills, an important factor is that the CI has to stimulate the auditory cortex. Obtaining behavioral measurements from young children with CIs can often be unreliable. While a variety of noninvasive techniques can be used for detecting cortical activity in response to auditory stimuli, many have critical limitations when applied to the pediatric CI population. We tested the ability of near-infrared spectroscopy (NIRS) to detect cortical responses to speech stimuli in pediatric CI users. Neuronal activity leads to changes in blood oxy- and deoxy-hemoglobin concentrations that can be detected by measuring the transmission of near-infrared light through the tissue. To verify the efficacy of NIRS, we first compared auditory cortex responses measured with NIRS and fMRI in normal-hearing adults. We then examined four different participant cohorts with NIRS alone. Speech-evoked cortical activity was observed in 100% of normal-hearing adults (11 of 11), 82% of normal-hearing children (9 of 11), 78% of deaf children who have used a CI > 4 months (28 of 36), and 78% of deaf children who completed NIRS testing on the day of CI initial activation (7 of 9). Therefore, NIRS can measure cortical responses in pediatric CI users, and has the potential to be a powerful adjunct to current CI assessment tools.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.