ArticleMethods in enzymology2010
3D visualization of HIV virions by cryoelectron tomography.
Article in Methods in enzymology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed.
- Electron cryotomography reveals ultrastructure alterations in platelets from patients with ovarian cancer.Proceedings of the National Academy of Sciences of the United States of America · 2015Trial
- Tailoring virus-inspired nanoparticles for advanced drug and gene delivery.Materials today. Bio · 2026Review
- Advances in viral vector-based delivery systems for gene therapy: a comprehensive review.3 Biotech · 2025Review
- Cryo-electron microscopy in the study of virus entry and infection.Frontiers in molecular biosciences · 2024Review
- In Situ Imaging of Virus-Infected Cells by Cryo-Electron Tomography: An Overview.Sub-cellular biochemistry · 2023Review
- Cryo-EM structures of prefusion SIV envelope trimer.Nature structural & molecular biology · 2022Article
- SARS-CoV-2 Portrayed against HIV: Contrary Viral Strategies in Similar Disguise.Microorganisms · 2021Review
- Subnanometer structures of HIV-1 envelope trimers on aldrithiol-2-inactivated virus particles.Nature structural & molecular biology · 2020Article
- Article
- Cryo-electron tomography of periplasmic flagella in Borrelia burgdorferi reveals a distinct cytoplasmic ATPase complex.PLoS biology · 2018Article
- Visualization of Assembly Intermediates and Budding Vacuoles of Singapore Grouper Iridovirus in Grouper Embryonic Cells.Scientific reports · 2016Article
- Structural remodeling of bacteriophage T4 and host membranes during infection initiation.Proceedings of the National Academy of Sciences of the United States of America · 2015Article
- Visualization of the type III secretion sorting platform of Shigella flexneri.Proceedings of the National Academy of Sciences of the United States of America · 2015Article
- Molecular architecture of the bacterial flagellar motor in cells.Biochemistry · 2014Review
- Cryoelectron tomography reveals the sequential assembly of bacterial flagella in Borrelia burgdorferi.Proceedings of the National Academy of Sciences of the United States of America · 2013Article
- Electron tomography of paracrystalline 2D arrays.Methods in molecular biology (Clifton, N.J.) · 2013Article
- Viral vectors for gene delivery to the central nervous system.Neurobiology of disease · 2012Review
- Molecular architecture of chemoreceptor arrays revealed by cryoelectron tomography of Escherichia coli minicells.Proceedings of the National Academy of Sciences of the United States of America · 2012Article
- The mechanism of DNA ejection in the Bacillus anthracis spore-binding phage 8a revealed by cryo-electron tomography.Virology · 2011Article
- Morphogenesis of the Infectious HIV-1 Virion.Frontiers in microbiology · 2011Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
The structure of the human immunodeficiency virus (HIV) and some of its components have been difficult to study in three-dimensions (3D) primarily because of their intrinsic structural variability. Recent advances in cryoelectron tomography (cryo-ET) have provided a new approach for determining the 3D structures of the intact virus, the HIV capsid, and the envelope glycoproteins located on the viral surface. A number of cryo-ET procedures related to specimen preservation, data collection, and image processing are presented in this chapter. The techniques described herein are well suited for determining the ultrastructure of bacterial and viral pathogens and their associated molecular machines in situ at nanometer resolution.
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